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Catalog Number:
41167
CAS Number:
74311-56-1
(R)-N,N-Dimethyl-1-[(S)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine
Purity:
≥ 98% (Chiral purity)
Synonym(s):
[R,R]-1-[1-Dimethylaminoethyl]-1',2-bis[diphenylphosphino]ferrocene, (R)-(S)-BPPFA
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$144.12 /100MG
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Product Information

(R)-N,N-Dimethyl-1-[(S)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine is a sophisticated chiral ligand that plays a pivotal role in asymmetric synthesis and catalysis. This compound is particularly valued in the field of organometallic chemistry, where it serves as a catalyst in various reactions, including cross-coupling and hydrogenation processes. Its unique structure, featuring a ferrocenyl backbone, enhances its stability and reactivity, making it an ideal choice for researchers looking to develop efficient synthetic pathways. The presence of diphenylphosphino groups further amplifies its effectiveness in coordinating with transition metals, thereby facilitating a range of catalytic transformations.

In practical applications, this compound has been utilized in the synthesis of pharmaceuticals and fine chemicals, where precise control over stereochemistry is crucial. Its ability to promote enantioselective reactions allows for the production of chiral molecules with high purity, which is essential in drug development. Additionally, the compound's robustness under various reaction conditions makes it a reliable choice for industrial applications, offering significant advantages over similar ligands in terms of efficiency and selectivity. Researchers and industry professionals will find (R)-N,N-Dimethyl-1-[(S)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine to be an invaluable tool in advancing their work in synthetic chemistry.

Synonyms
[R,R]-1-[1-Dimethylaminoethyl]-1',2-bis[diphenylphosphino]ferrocene, (R)-(S)-BPPFA
CAS Number
74311-56-1
Purity
≥ 98% (Chiral purity)
Molecular Formula
C38H37FeNP2
Molecular Weight
625.51
MDL Number
MFCD00075284
Melting Point
138 - 144 °C
Appearance
Light yellow to brown crystal
Optical Rotation
[α]20D = -360 to -330 ° (C = 0.5 in CHCl3)
Conditions
Store at RT
General Information
Synonyms
[R,R]-1-[1-Dimethylaminoethyl]-1',2-bis[diphenylphosphino]ferrocene, (R)-(S)-BPPFA
CAS Number
74311-56-1
Purity
≥ 98% (Chiral purity)
Molecular Formula
C38H37FeNP2
Molecular Weight
625.51
MDL Number
MFCD00075284
Melting Point
138 - 144 °C
Appearance
Light yellow to brown crystal
Optical Rotation
[α]20D = -360 to -330 ° (C = 0.5 in CHCl3)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-N,N-Dimethyl-1-[(S)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine is widely utilized in research focused on:

  • Catalysis: This compound serves as a chiral ligand in asymmetric catalysis, enhancing the selectivity and efficiency of chemical reactions in pharmaceutical synthesis.
  • Organometallic Chemistry: Its unique structure allows it to stabilize metal complexes, making it valuable in the development of new materials and catalysts.
  • Drug Development: Researchers leverage its properties to design and synthesize novel drug candidates, particularly in the field of anticancer therapies.
  • Analytical Chemistry: It is used in the development of sensors and probes for detecting specific biomolecules, improving the accuracy of analytical methods.
  • Green Chemistry: The compound contributes to more sustainable practices by enabling reactions that reduce waste and energy consumption compared to traditional methods.

Citations