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Catalog Number:
31475
CAS Number:
1070663-78-3
Brettphos
Purity:
≥ 98% (HPLC)
Synonym(s):
2-(Dicyclohexylphosphino)3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl
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Product Information

Brettphos is a versatile phosphine ligand known for its unique structural properties and exceptional reactivity, making it an invaluable asset in various chemical applications. With its dicyclohexyl backbone and triisopropylphenyl substituents, Brettphos exhibits remarkable stability and selectivity in catalytic processes. This compound is particularly effective in facilitating cross-coupling reactions, such as Suzuki and Heck reactions, which are essential in the synthesis of complex organic molecules. Its ability to enhance reaction rates while providing high yields makes it a preferred choice among researchers and industry professionals in the fields of pharmaceuticals, agrochemicals, and materials science.

In addition to its catalytic applications, Brettphos is also recognized for its role in the development of advanced materials and ligands in coordination chemistry. Its unique electronic properties allow for fine-tuning in various reactions, providing a competitive edge over similar phosphine ligands. By incorporating Brettphos into your research or production processes, you can achieve greater efficiency and precision, ultimately leading to innovative solutions in your projects.

Synonyms
2-(Dicyclohexylphosphino)3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl
CAS Number
1070663-78-3
Purity
≥ 98% (HPLC)
Molecular Formula
C35H53O2P
Molecular Weight
536.78
MDL Number
MFCD11973797
PubChem ID
25112535
Melting Point
187 - 195 °C
Appearance
Off-white to white solid
Conditions
Store at 0-8 °C
General Information
Synonyms
2-(Dicyclohexylphosphino)3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl
CAS Number
1070663-78-3
Purity
≥ 98% (HPLC)
Molecular Formula
C35H53O2P
Molecular Weight
536.78
MDL Number
MFCD11973797
PubChem ID
25112535
Melting Point
187 - 195 °C
Appearance
Off-white to white solid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Brettphos is widely utilized in research focused on various applications across different industries. Here are five practical uses:

  • Catalysis in Organic Synthesis: Brettphos serves as a highly effective ligand in catalytic processes, particularly in palladium-catalyzed cross-coupling reactions. This is crucial in the pharmaceutical industry for synthesizing complex organic molecules.
  • Development of New Materials: Its unique properties make it valuable in the development of advanced materials, including polymers and nanomaterials, enhancing their performance and stability.
  • Environmental Applications: The compound is used in processes aimed at reducing environmental impact, such as in the development of greener chemical reactions that minimize waste and energy consumption.
  • Research in Coordination Chemistry: Brettphos is employed in studies related to coordination compounds, helping researchers understand metal-ligand interactions, which is vital for designing new catalysts.
  • Pharmaceutical Research: Its role in drug discovery is significant, as it aids in the synthesis of bioactive compounds, streamlining the development of new therapeutic agents.

These applications highlight the versatility and importance of Brettphos in various fields, providing researchers and industry professionals with effective solutions to their challenges.

Citations