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Catalog Number:
41080
CAS Number:
259212-61-8
trans-4-(tert-Butyldiphenylsilyloxy)-L-proline
Purity:
≥ 98% (HPLC)
Synonym(s):
(2S,4R)-4-(tert-Butyldiphenylsilyloxy)pyrrolidine-2-carboxylicacid
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Product Information

trans-4-(tert-Butyldiphenylsilyloxy)-L-proline is a versatile compound widely utilized in organic synthesis and pharmaceutical research. This compound features a unique tert-butyldiphenylsilyl group, which enhances its stability and solubility, making it an excellent candidate for various applications in medicinal chemistry. Its structural characteristics allow for effective incorporation into peptide synthesis, facilitating the development of novel therapeutic agents. Researchers have found that this compound can serve as a valuable building block in the design of bioactive molecules, particularly in the creation of proline derivatives that exhibit significant biological activity.

In addition to its role in synthetic chemistry, trans-4-(tert-Butyldiphenylsilyloxy)-L-proline is also recognized for its potential in drug formulation and delivery systems. Its unique properties enable improved interaction with biological targets, which can lead to enhanced efficacy and reduced side effects in therapeutic applications. This compound is particularly beneficial for researchers focused on developing new treatments for various diseases, as it provides a reliable and efficient pathway for the synthesis of complex molecular structures.

Synonyms
(2S,4R)-4-(tert-Butyldiphenylsilyloxy)pyrrolidine-2-carboxylicacid
CAS Number
259212-61-8
Purity
≥ 98% (HPLC)
Molecular Formula
C21H27NO3Si
Molecular Weight
369.54
MDL Number
MFCD12407126
PubChem ID
71317354
Melting Point
198 °C (dec.)
Appearance
White to off-white crystal
Optical Rotation
[α]20D = -35.0 to -34.0 ° (C = 0.8 in MeOH)
Conditions
Store at RT
General Information
Synonyms
(2S,4R)-4-(tert-Butyldiphenylsilyloxy)pyrrolidine-2-carboxylicacid
CAS Number
259212-61-8
Purity
≥ 98% (HPLC)
Molecular Formula
C21H27NO3Si
Molecular Weight
369.54
MDL Number
MFCD12407126
PubChem ID
71317354
Melting Point
198 °C (dec.)
Appearance
White to off-white crystal
Optical Rotation
[α]20D = -35.0 to -34.0 ° (C = 0.8 in MeOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

trans-4-(tert-Butyldiphenylsilyloxy)-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, offering enhanced stability and solubility compared to traditional amino acids.
  • Drug Development: It is employed in the design of novel pharmaceuticals, particularly in creating prodrugs that improve bioavailability and therapeutic efficacy.
  • Bioconjugation: The compound is used in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in diagnostics and targeted therapies.
  • Material Science: In the field of material science, it is utilized to modify polymers, enhancing their mechanical properties and thermal stability for various applications.
  • Research in Neuroscience: This chemical is involved in studies related to neuroprotective agents, helping to develop treatments for neurodegenerative diseases by improving the delivery of therapeutic compounds to the brain.

Citations