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Catalog Number:
41077
CAS Number:
848821-58-9
(S-(-)-α,α-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether
Purity:
≥ 99.5% (Chiral GC)
Synonym(s):
(S-(-)-2-[Diphenyl(trimethylsilyloxy)methyl]pyrrolidine, a,α-Diphenyl-L-prolinol Trimethylsilyl Ether, (S-Hayashi-Jorgensen catalyst
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Product Information

(S)-(-)-a,a-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether is a versatile compound widely utilized in organic synthesis and pharmaceutical research. This compound, characterized by its unique trimethylsilyl ether functional group, enhances the solubility and stability of various organic molecules, making it an invaluable tool for chemists. Its chiral nature allows for the synthesis of enantiomerically pure compounds, which is crucial in the development of pharmaceuticals where stereochemistry plays a significant role in biological activity.

Researchers have leveraged this compound in the synthesis of complex organic molecules, particularly in the field of medicinal chemistry, where it aids in the development of new therapeutic agents. Its ability to act as a protecting group for alcohols during chemical reactions further underscores its importance in synthetic pathways. With its unique properties, (S)-(-)-a,a-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether stands out as a reliable choice for professionals seeking efficiency and precision in their chemical processes.

Synonyms
(S-(-)-2-[Diphenyl(trimethylsilyloxy)methyl]pyrrolidine, a,α-Diphenyl-L-prolinol Trimethylsilyl Ether, (S-Hayashi-Jorgensen catalyst
CAS Number
848821-58-9
Purity
≥ 99.5% (Chiral GC)
Molecular Formula
C20H27NOSi
Molecular Weight
325.53
MDL Number
MFCD08690083
PubChem ID
23629008
Density
1.04 g/mL
Appearance
Pale yellow oil
Refractive Index
n20D 1.55
Optical Rotation
[a]20D = -54 to -48 ° (C = 1 in CHCl3)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(S-(-)-2-[Diphenyl(trimethylsilyloxy)methyl]pyrrolidine, a,α-Diphenyl-L-prolinol Trimethylsilyl Ether, (S-Hayashi-Jorgensen catalyst
CAS Number
848821-58-9
Purity
≥ 99.5% (Chiral GC)
Molecular Formula
C20H27NOSi
Molecular Weight
325.53
MDL Number
MFCD08690083
PubChem ID
23629008
Density
1.04 g/mL
Appearance
Pale yellow oil
Refractive Index
n20D 1.55
Optical Rotation
[a]20D = -54 to -48 ° (C = 1 in CHCl3)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(-)-a,a-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether is widely utilized in research focused on:

  • Synthetic Organic Chemistry: This compound serves as a versatile building block in the synthesis of complex organic molecules, enabling researchers to explore new chemical pathways and develop innovative products.
  • Pharmaceutical Development: It is used in the formulation of pharmaceutical compounds, particularly in the design of drugs that target specific biological pathways, enhancing efficacy and reducing side effects.
  • Material Science: The compound finds applications in creating advanced materials, such as polymers and coatings, which benefit from its unique chemical properties, improving durability and performance.
  • Analytical Chemistry: It acts as a reagent in various analytical techniques, aiding in the identification and quantification of other chemical substances, thus streamlining research processes.
  • Biotechnology: The compound is leveraged in bioconjugation strategies, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial for developing biosensors and targeted drug delivery systems.

Citations