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Catalog Number:
40783
CAS Number:
106681-15-6
Ru(OAc)2[(S)-tolbinap]
Synonym(s):
Diacetato[(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl]ruthenium(II)
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$65.40 /200MG
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Product Information

Ru(OAc)2[(S)-tolbinap] is a versatile ruthenium-based catalyst known for its significant role in various organic transformations, particularly in asymmetric synthesis. This compound is recognized for its ability to facilitate reactions such as hydrogenation and cross-coupling, making it an invaluable tool for researchers and industry professionals focused on developing chiral compounds. Its unique structure, featuring a ruthenium center coordinated with acetate ligands and a chiral phosphine ligand, enhances its reactivity and selectivity, allowing for the efficient production of pharmaceuticals and fine chemicals.

The practical applications of Ru(OAc)2[(S)-tolbinap] extend to the synthesis of complex molecules in medicinal chemistry, where the need for enantiomerically pure compounds is paramount. Its effectiveness in catalyzing reactions under mild conditions not only improves yields but also minimizes by-products, making it a preferred choice in sustainable chemistry practices. Researchers can leverage this catalyst to streamline their workflows, reduce waste, and achieve high levels of precision in their synthetic endeavors.

Synonyms
Diacetato[(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl]ruthenium(II)
CAS Number
106681-15-6
Molecular Formula
C52H46O4P2Ru
Molecular Weight
897.95
MDL Number
MFCD09753021
PubChem ID
11007467
Appearance
Dark green, dark red or black crystalline powder
Optical Rotation
[α]20D = -1140 to -940 ° (C = 0.5 in Chloroform)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Diacetato[(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl]ruthenium(II)
CAS Number
106681-15-6
Molecular Formula
C52H46O4P2Ru
Molecular Weight
897.95
MDL Number
MFCD09753021
PubChem ID
11007467
Appearance
Dark green, dark red or black crystalline powder
Optical Rotation
[α]20D = -1140 to -940 ° (C = 0.5 in Chloroform)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ru(OAc)2[(S)-tolbinap] is widely utilized in research focused on:

  • Catalysis: This compound serves as an efficient catalyst in various organic reactions, particularly in asymmetric synthesis, allowing for the production of chiral molecules that are crucial in pharmaceuticals.
  • Pharmaceutical Development: Its ability to facilitate complex reactions makes it valuable in the development of new drugs, enhancing the efficiency of synthesizing active pharmaceutical ingredients (APIs).
  • Material Science: The compound is used in the creation of advanced materials, such as polymers and nanomaterials, which have applications in electronics and coatings.
  • Environmental Chemistry: It plays a role in green chemistry initiatives by promoting reactions that minimize waste and reduce the use of hazardous solvents, aligning with sustainable practices.
  • Research and Academia: Widely adopted in academic laboratories for teaching and research purposes, it provides students and researchers with hands-on experience in modern synthetic techniques.

Citations