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Catalog Number:
31875
CAS Number:
564483-19-8
tBuXPhos
Purity:
≥ 98% (Assay)
Synonym(s):
2-Di-tert-butylphosphino-2',4',6'-triisopropylbiphenyl, t-Bu Xphos, tert-Butyl Xphos
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Product Information

tBuXPhos is a highly versatile phosphine ligand that plays a crucial role in various catalytic processes, particularly in the field of organic synthesis. Known for its sterically hindered structure, tBuXPhos enhances the selectivity and efficiency of palladium-catalyzed reactions, making it an invaluable tool for chemists working on cross-coupling reactions such as Suzuki and Heck reactions. Its unique properties allow for improved yields and reduced by-product formation, which are essential for both academic research and industrial applications.

This compound is particularly favored in the pharmaceutical and agrochemical industries, where precision and efficiency are paramount. Researchers have successfully utilized tBuXPhos in the development of complex molecules, streamlining synthetic pathways and accelerating the discovery of new compounds. Its robust nature and compatibility with various reaction conditions further solidify its position as a go-to ligand for chemists seeking reliable and effective solutions in their synthetic endeavors.

Synonyms
2-Di-tert-butylphosphino-2',4',6'-triisopropylbiphenyl, t-Bu Xphos, tert-Butyl Xphos
CAS Number
564483-19-8
Purity
≥ 98% (Assay)
Molecular Formula
C29H45P
Molecular Weight
424.65
MDL Number
MFCD06411306
PubChem ID
11618717
Melting Point
147 - 151 °C
Appearance
White to off-white solid
Conditions
Store at 0 - 8 ºC
General Information
Synonyms
2-Di-tert-butylphosphino-2',4',6'-triisopropylbiphenyl, t-Bu Xphos, tert-Butyl Xphos
CAS Number
564483-19-8
Purity
≥ 98% (Assay)
Molecular Formula
C29H45P
Molecular Weight
424.65
MDL Number
MFCD06411306
PubChem ID
11618717
Melting Point
147 - 151 °C
Appearance
White to off-white solid
Conditions
Store at 0 - 8 ºC
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

tBuXPhos is widely utilized in research focused on:

  • Catalysis: This compound serves as a highly effective ligand in various catalytic reactions, particularly in palladium-catalyzed cross-coupling processes. Its steric properties enhance reaction selectivity and yield.
  • Organic Synthesis: Researchers leverage tBuXPhos for synthesizing complex organic molecules, benefiting from its ability to stabilize reactive intermediates and improve reaction rates.
  • Pharmaceutical Development: In the pharmaceutical industry, it aids in the development of new drugs by facilitating the formation of carbon-carbon bonds, which is crucial for constructing diverse molecular architectures.
  • Material Science: The compound is also applied in the development of advanced materials, including polymers and nanomaterials, due to its unique electronic properties and ability to enhance material performance.
  • Green Chemistry: tBuXPhos contributes to more sustainable practices by enabling reactions that require milder conditions, thus reducing the environmental impact compared to traditional methods.

Citations