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Catalog Number:
31872
CAS Number:
251320-86-2
MePhos
Purity:
≥ 98% (HPLC)
Synonym(s):
2-Dicyclohexylphosphino-2'-methylbiphenyl, 2-Methyl-2'-dicyclohexylphosphinobiphenyl, MebiphPCy2
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$22.03 /1G
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Product Information

MePhos is a highly versatile phosphine ligand known for its exceptional properties in catalysis and organic synthesis. This compound, characterized by its dicyclohexyl and 2-(2-methylphenyl)phenyl structure, offers unique steric and electronic characteristics that enhance its performance in various chemical reactions. Researchers and industry professionals utilize MePhos primarily in palladium-catalyzed cross-coupling reactions, such as Suzuki and Heck reactions, where it significantly improves yields and selectivity. Its ability to stabilize palladium complexes makes it an invaluable tool in the development of pharmaceuticals and advanced materials.

In addition to its catalytic applications, MePhos is also recognized for its role in asymmetric synthesis, providing pathways to chiral compounds that are essential in the production of fine chemicals and agrochemicals. The compound's robust nature and compatibility with a wide range of substrates make it a preferred choice for chemists seeking reliable and efficient solutions in their synthetic endeavors. With its proven track record in enhancing reaction efficiency, MePhos stands out as a key player in modern chemical research and industrial applications.

Synonyms
2-Dicyclohexylphosphino-2'-methylbiphenyl, 2-Methyl-2'-dicyclohexylphosphinobiphenyl, MebiphPCy2
CAS Number
251320-86-2
Purity
≥ 98% (HPLC)
Molecular Formula
C25H33P
Molecular Weight
364.5
MDL Number
MFCD03094577
PubChem ID
2734938
Melting Point
107 - 111 °C
Appearance
White powder
Conditions
Store at 0-8 ºC
General Information
Synonyms
2-Dicyclohexylphosphino-2'-methylbiphenyl, 2-Methyl-2'-dicyclohexylphosphinobiphenyl, MebiphPCy2
CAS Number
251320-86-2
Purity
≥ 98% (HPLC)
Molecular Formula
C25H33P
Molecular Weight
364.5
MDL Number
MFCD03094577
PubChem ID
2734938
Melting Point
107 - 111 °C
Appearance
White powder
Conditions
Store at 0-8 ºC
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

MePhos is widely utilized in research focused on:

  • Catalysis: It serves as an effective ligand in various catalytic processes, particularly in cross-coupling reactions, enhancing reaction rates and selectivity.
  • Pharmaceutical Development: Its unique properties make it valuable in the synthesis of complex organic molecules, aiding in the development of new drugs.
  • Material Science: MePhos is used in the formulation of advanced materials, contributing to the creation of polymers with improved mechanical and thermal properties.
  • Environmental Chemistry: It plays a role in the development of green chemistry practices, helping to reduce waste and improve the efficiency of chemical processes.
  • Research and Development: MePhos is a key component in academic and industrial research, facilitating the exploration of new chemical pathways and reactions.

Citations