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Catalog Number:
45823
CAS Number:
157911-56-3
2,4,5-Trifluorobenzyl bromide
Purity:
≥ 98% (GC)
Synonym(s):
1-(Bromomethyl)-2,4,5-trifluorobenzene
Hazmat
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Product Information

2,4,5-Trifluorobenzyl bromide is a versatile chemical compound known for its unique trifluoromethyl group, which enhances its reactivity and utility in various applications. This compound serves as a crucial intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Its ability to introduce trifluoromethyl groups into organic molecules makes it particularly valuable in the development of fluorinated compounds, which are often associated with improved biological activity and stability. Researchers and industry professionals utilize 2,4,5-Trifluorobenzyl bromide for the synthesis of complex molecules, including those used in medicinal chemistry and material science.

In addition to its synthetic applications, 2,4,5-Trifluorobenzyl bromide is recognized for its role in enhancing the properties of final products, such as increased lipophilicity and metabolic stability. This compound is particularly advantageous compared to similar brominated compounds due to its trifluoromethyl substitution, which can lead to more favorable pharmacokinetic profiles in drug development. Its unique properties and applications make it an essential choice for chemists looking to innovate in their respective fields.

Synonyms
1-(Bromomethyl)-2,4,5-trifluorobenzene
CAS Number
157911-56-3
Purity
≥ 98% (GC)
Molecular Formula
C7H4BrF3
Molecular Weight
225.01
MDL Number
MFCD00061209
PubChem ID
2777057
Melting Point
10 - 13 °C
Density
1.71
Appearance
Colorless to light yellow clear liquid
Refractive Index
n20D 1.51
Conditions
Store at RT
General Information
Synonyms
1-(Bromomethyl)-2,4,5-trifluorobenzene
CAS Number
157911-56-3
Purity
≥ 98% (GC)
Molecular Formula
C7H4BrF3
Molecular Weight
225.01
MDL Number
MFCD00061209
PubChem ID
2777057
Melting Point
10 - 13 °C
Density
1.71
Appearance
Colorless to light yellow clear liquid
Refractive Index
n20D 1.51
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,4,5-Trifluorobenzyl bromide is widely utilized in research focused on:

  • Synthetic Chemistry: This compound serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, allowing researchers to create complex molecules efficiently.
  • Fluorinated Compounds: Its unique trifluoromethyl group enhances the biological activity of compounds, making it valuable in the development of new drugs with improved efficacy and selectivity.
  • Material Science: Used in the production of fluorinated polymers, it contributes to materials with enhanced thermal stability and chemical resistance, which are essential in high-performance applications.
  • Bioconjugation: The bromide functionality allows for easy attachment to biomolecules, facilitating the creation of targeted drug delivery systems and diagnostic agents in biomedicine.
  • Research Reagents: As a versatile reagent, it is employed in various chemical reactions, providing researchers with a reliable tool for exploring new chemical pathways and reactions.

Citations