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Catalog Number:
44862
CAS Number:
1820-81-1
5-Chlorouracil
Purity:
≥ 98% (Assay by titration)
Documents
$84.53 /5G
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Product Information

5-Chlorouracil is a halogenated derivative of uracil, recognized for its significant role in pharmaceutical applications, particularly in cancer treatment. This compound exhibits potent antitumor activity, making it a valuable agent in the development of chemotherapeutic drugs. Its mechanism of action involves the inhibition of DNA synthesis, which is crucial for the proliferation of cancer cells. Researchers and industry professionals utilize 5-Chlorouracil in various formulations aimed at targeting specific types of tumors, enhancing the efficacy of treatment regimens.

In addition to its therapeutic applications, 5-Chlorouracil serves as a key intermediate in the synthesis of other biologically active compounds, expanding its utility in medicinal chemistry. Its unique properties, such as its ability to selectively inhibit certain enzymes involved in nucleic acid metabolism, provide a competitive edge over similar compounds. This makes it an essential tool for researchers focused on developing innovative treatments and understanding cellular mechanisms in oncology.

CAS Number
1820-81-1
Purity
≥ 98% (Assay by titration)
Molecular Formula
C4H3ClN2O2
Molecular Weight
146.53
MDL Number
MFCD00006019
PubChem ID
15758
Melting Point
>300 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
General Information
CAS Number
1820-81-1
Purity
≥ 98% (Assay by titration)
Molecular Formula
C4H3ClN2O2
Molecular Weight
146.53
MDL Number
MFCD00006019
PubChem ID
15758
Melting Point
>300 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Chlorouracil is widely utilized in research focused on:

  • Cancer Treatment: This compound is used as a chemotherapeutic agent, particularly in the treatment of certain types of cancer. Its ability to inhibit DNA synthesis makes it effective against rapidly dividing cancer cells.
  • Antiviral Research: It serves as a valuable tool in the development of antiviral medications. Researchers explore its efficacy against viral infections, leveraging its mechanism to disrupt viral replication.
  • Biochemical Studies: In laboratories, 5-Chlorouracil is employed to study nucleic acid metabolism and the effects of pyrimidine analogs on cellular processes, aiding in the understanding of genetic regulation.
  • Pharmaceutical Development: The compound is used in the formulation of various drugs, allowing pharmaceutical companies to create targeted therapies that minimize side effects while maximizing therapeutic effects.
  • Genetic Research: It is utilized in genetic engineering and molecular biology to induce mutations, helping scientists understand gene function and regulation in various organisms.

Citations