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Catalog Number:
44695
CAS Number:
444120-94-9
2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Purity:
≥ 98% (GC)
Synonym(s):
2-(6-Chloro-3-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-Chloropyridine-5-boronic acid pinacol ester
Documents
$71.41 /1G
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Product Information

2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a versatile compound that plays a significant role in organic synthesis and medicinal chemistry. This compound is particularly valued for its ability to serve as a building block in the development of various pharmaceuticals and agrochemicals. Its unique structure, featuring a chloro group and a dioxaborolane moiety, enhances its reactivity and compatibility with a wide range of functional groups, making it an essential intermediate in the synthesis of complex molecules. Researchers and industry professionals can leverage its properties for applications in cross-coupling reactions, which are pivotal in the formation of carbon-carbon bonds, thereby facilitating the creation of diverse chemical entities.

Moreover, the presence of the dioxaborolane group not only contributes to the compound's stability but also allows for easy manipulation in synthetic pathways, offering a strategic advantage over similar compounds. This characteristic makes it an attractive option for chemists looking to streamline their synthesis processes while achieving high yields. Whether in the laboratory or industrial settings, 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine stands out as a valuable asset for advancing research and development in various chemical domains.

Synonyms
2-(6-Chloro-3-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-Chloropyridine-5-boronic acid pinacol ester
CAS Number
444120-94-9
Purity
≥ 98% (GC)
Molecular Formula
C11H15BClNO2
Molecular Weight
239.51
MDL Number
MFCD03412793
PubChem ID
2794719
Melting Point
85 - 89 °C
Density
1.14
Appearance
White to almost white powder to crystal
Boiling Point
328 - 344 °C
Refractive Index
n20D 1.50
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-(6-Chloro-3-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-Chloropyridine-5-boronic acid pinacol ester
CAS Number
444120-94-9
Purity
≥ 98% (GC)
Molecular Formula
C11H15BClNO2
Molecular Weight
239.51
MDL Number
MFCD03412793
PubChem ID
2794719
Melting Point
85 - 89 °C
Density
1.14
Appearance
White to almost white powder to crystal
Boiling Point
328 - 344 °C
Refractive Index
n20D 1.50
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly those targeting neurological disorders, enhancing drug efficacy.
  • Organic Synthesis: It is employed as a versatile building block in organic chemistry, facilitating the formation of complex molecules with high precision and yield.
  • Material Science: The compound is used in the development of advanced materials, including polymers and coatings, which exhibit improved durability and chemical resistance.
  • Agricultural Chemistry: It finds application in creating agrochemicals, contributing to the formulation of effective pesticides and herbicides that are safer for the environment.
  • Research and Development: In academic settings, it is utilized in various research projects aimed at exploring new chemical reactions and mechanisms, providing valuable insights into molecular behavior.

Citations