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Catalog Number:
07254
CAS Number:
456-41-7
3-fluorobenzyl bromide
Purity:
≥ 98%
Synonym(s):
α-bromo-3-fluorotoluene
Hazmat
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Product Information

3-fluorobenzyl bromide is a versatile chemical compound widely utilized in organic synthesis and pharmaceutical research. This compound, characterized by its unique fluorine substitution, serves as a valuable intermediate in the production of various pharmaceuticals and agrochemicals. Its reactivity allows for the introduction of the 3-fluorobenzyl group into target molecules, making it an essential building block in the development of novel therapeutic agents. Researchers appreciate its ability to enhance the biological activity of compounds, particularly in the design of selective inhibitors and other bioactive molecules.

In addition to its applications in drug discovery, 3-fluorobenzyl bromide is also employed in the synthesis of advanced materials and specialty chemicals. Its unique properties facilitate the creation of functionalized polymers and ligands, which are crucial in catalysis and materials science. The compound's stability and compatibility with various reaction conditions further enhance its utility in diverse chemical processes. With its broad range of applications, 3-fluorobenzyl bromide stands out as a key reagent for professionals seeking to innovate in their respective fields.

Synonyms
α-bromo-3-fluorotoluene
CAS Number
456-41-7
Purity
≥ 98%
Molecular Formula
C7H6BrF
Molecular Weight
189.0
MDL Number
MFCD00000340
PubChem ID
68007
Density
1.541
Appearance
Colorless to pale yellow to yellow liquid
Boiling Point
88 ºC / 20 mmHg
Refractive Index
1.546
Conditions
Store at 0 - 8 °C
General Information
Synonyms
α-bromo-3-fluorotoluene
CAS Number
456-41-7
Purity
≥ 98%
Molecular Formula
C7H6BrF
Molecular Weight
189.0
MDL Number
MFCD00000340
PubChem ID
68007
Density
1.541
Appearance
Colorless to pale yellow to yellow liquid
Boiling Point
88 ºC / 20 mmHg
Refractive Index
1.546
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-fluorobenzyl bromide is widely utilized in research focused on:

  • Synthetic Chemistry: It serves as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, enabling researchers to develop new drugs and crop protection agents.
  • Pharmaceutical Development: This compound is used in the creation of fluorinated compounds, which often exhibit enhanced biological activity, making it valuable in drug discovery and development processes.
  • Material Science: It is employed in the production of specialty polymers and resins, contributing to the development of advanced materials with unique properties for applications in electronics and coatings.
  • Bioconjugation: The bromide group allows for easy attachment to biomolecules, facilitating the design of targeted drug delivery systems and diagnostic tools in biomedical research.
  • Fluorine Chemistry: Its fluorine atom enhances the lipophilicity of compounds, improving their pharmacokinetic profiles, which is crucial for optimizing drug formulations.

Citations