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Catalog Number:
41594
CAS Number:
42437-96-7
(R)-(-)-3-Quinuclidinol hydrochloride
Purity:
96 - 101% (Assay by titration)
Synonym(s):
(R)-(-)-3-Hydroxyquinuclidine hydrochloride
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Product Information

(R)-(-)-3-Quinuclidinol hydrochloride is a versatile compound recognized for its significant role in medicinal chemistry and pharmacology. This chiral bicyclic amine is primarily utilized as a precursor in the synthesis of various pharmaceuticals, particularly in the development of analgesics and antispasmodics. Its unique structure allows for the modulation of biological activity, making it a valuable asset in drug formulation. Researchers appreciate its potential in the synthesis of compounds that target the central nervous system, providing avenues for the treatment of pain and muscle spasms.

In addition to its pharmaceutical applications, (R)-(-)-3-Quinuclidinol hydrochloride serves as a chiral building block in asymmetric synthesis, facilitating the creation of enantiomerically pure compounds. This characteristic is particularly beneficial in the production of drugs where stereochemistry is crucial for efficacy and safety. With its established utility in both research and industry, this compound stands out for its ability to enhance the development of innovative therapeutic agents.

Synonyms
(R)-(-)-3-Hydroxyquinuclidine hydrochloride
CAS Number
42437-96-7
Purity
96 - 101% (Assay by titration)
Molecular Formula
C7H13NO·HCl
Molecular Weight
163.65
MDL Number
MFCD00270837
PubChem ID
2723725
Melting Point
344 - 350 °C (Lit.)
Appearance
White to off-white crystaline powder
Optical Rotation
[á]20/D = -35 ° (C = 1 in H2O)
Conditions
Store at RT
General Information
Synonyms
(R)-(-)-3-Hydroxyquinuclidine hydrochloride
CAS Number
42437-96-7
Purity
96 - 101% (Assay by titration)
Molecular Formula
C7H13NO·HCl
Molecular Weight
163.65
MDL Number
MFCD00270837
PubChem ID
2723725
Melting Point
344 - 350 °C (Lit.)
Appearance
White to off-white crystaline powder
Optical Rotation
[á]20/D = -35 ° (C = 1 in H2O)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(-)-3-Quinuclidinol hydrochloride is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of analgesics and anti-inflammatory drugs, enhancing their efficacy.
  • Neuroscience Research: It is used in studies related to neurotransmitter systems, helping researchers understand the mechanisms of action for certain central nervous system drugs.
  • Chiral Catalysis: The compound plays a role in asymmetric synthesis, acting as a chiral catalyst that improves the selectivity and yield of chemical reactions, which is crucial in producing enantiomerically pure compounds.
  • Analytical Chemistry: It is employed as a reference standard in analytical methods such as HPLC and GC, ensuring accurate quantification and identification of related compounds in complex mixtures.
  • Material Science: The compound is explored for its potential applications in developing new materials, particularly in creating polymers with specific properties, benefiting industries like coatings and adhesives.

Citations