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Catalog Number:
41593
CAS Number:
307531-88-0
(S)-(+)-N-Boc-3-N-Fmoc-aminopyrrolidine
Purity:
≥ 97% (HPLC)
Synonym(s):
(S)-(+)-1-(tert-Butoxycarbonyl)-3-N-(9-fluorenylmethoxycarbonyl)aminopyrrolidine
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Product Information

(S)-(+)-N-Boc-3-N-Fmoc-aminopyrrolidine is a versatile compound widely utilized in the fields of medicinal chemistry and peptide synthesis. This compound features a tert-butyl protective group and a fluorenylmethoxycarbonyl (Fmoc) moiety, making it an excellent choice for the protection of amines during synthetic procedures. Its unique structure allows for selective reactions, facilitating the development of complex molecules in pharmaceutical research. Researchers appreciate its stability under various conditions, which enhances its utility in multi-step synthesis processes.

This compound is particularly beneficial in the synthesis of bioactive peptides and other nitrogen-containing heterocycles. Its ability to serve as a building block in the preparation of peptide libraries makes it invaluable for drug discovery and development. Additionally, (S)-(+)-N-Boc-3-N-Fmoc-aminopyrrolidine's compatibility with various coupling reagents and its ease of deprotection further streamline the synthesis workflow, providing significant advantages over similar compounds.

Synonyms
(S)-(+)-1-(tert-Butoxycarbonyl)-3-N-(9-fluorenylmethoxycarbonyl)aminopyrrolidine
CAS Number
307531-88-0
Purity
≥ 97% (HPLC)
Molecular Formula
C24H28N2O4
Molecular Weight
408.49
MDL Number
MFCD07369742
PubChem ID
3649546
Melting Point
172 - 180 °C (dec.)
Appearance
White to off-white crystaline powder
Optical Rotation
[á]20/D = 6 ± 3 ° (C = 1 in Chloroform)
Conditions
Store at ≤ -10 °C
General Information
Synonyms
(S)-(+)-1-(tert-Butoxycarbonyl)-3-N-(9-fluorenylmethoxycarbonyl)aminopyrrolidine
CAS Number
307531-88-0
Purity
≥ 97% (HPLC)
Molecular Formula
C24H28N2O4
Molecular Weight
408.49
MDL Number
MFCD07369742
PubChem ID
3649546
Melting Point
172 - 180 °C (dec.)
Appearance
White to off-white crystaline powder
Optical Rotation
[á]20/D = 6 ± 3 ° (C = 1 in Chloroform)
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(+)-N-Boc-3-N-Fmoc-aminopyrrolidine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences efficiently.
  • Drug Development: It plays a crucial role in pharmaceutical research, especially in the development of new drugs targeting various diseases, due to its ability to enhance the stability and bioavailability of active pharmaceutical ingredients.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to drugs or imaging agents, improving their targeting and efficacy in therapeutic applications.
  • Research in Neuroscience: This chemical is valuable in neuroscience research for the synthesis of compounds that can modulate neurotransmitter systems, potentially leading to new treatments for neurological disorders.
  • Material Science: It is also applied in the development of functional materials, where its unique properties can be harnessed to create innovative polymers or coatings with specific functionalities.

Citations