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Catalog Number:
41587
CAS Number:
131878-23-4
(R)-(+)-1-Benzyl-3-(Boc-amino)pyrrolidine
Purity:
≥ 98% (GC)
Synonym(s):
(R)-(+)-1-Benzyl-3-(tert-butoxycarbonylamino)pyrrolidine
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Product Information

(R)-(+)-1-Benzyl-3-(Boc-amino)pyrrolidine is a versatile compound widely utilized in the fields of medicinal chemistry and pharmaceutical research. This chiral pyrrolidine derivative is particularly valued for its role as a building block in the synthesis of various bioactive molecules, including potential therapeutic agents. Its unique structure, featuring a benzyl group and a tert-butoxycarbonyl (Boc) protecting group, enhances its reactivity and stability, making it an ideal candidate for peptide synthesis and other complex organic transformations. Researchers appreciate its ability to facilitate the development of novel compounds with improved efficacy and selectivity in drug design.

In addition to its applications in synthetic chemistry, (R)-(+)-1-Benzyl-3-(Boc-amino)pyrrolidine is also significant in the study of chiral catalysts and asymmetric synthesis. Its chirality allows for the production of enantiomerically pure compounds, which is crucial in the pharmaceutical industry to ensure the desired therapeutic effects while minimizing side effects. This compound stands out for its potential to streamline the synthesis of complex molecules, making it a valuable asset for researchers and industry professionals aiming to innovate in drug development and chemical synthesis.

Synonyms
(R)-(+)-1-Benzyl-3-(tert-butoxycarbonylamino)pyrrolidine
CAS Number
131878-23-4
Purity
≥ 98% (GC)
Molecular Formula
C16H24N2O2
Molecular Weight
276.37
MDL Number
MFCD01321148
PubChem ID
3575823
Melting Point
77 - 81 °C (Lit.)
Appearance
White to off-white crystaline powder
Optical Rotation
[á]20/D = 6 ° (C = 1 in Chloroform)
Conditions
Store at RT
General Information
Synonyms
(R)-(+)-1-Benzyl-3-(tert-butoxycarbonylamino)pyrrolidine
CAS Number
131878-23-4
Purity
≥ 98% (GC)
Molecular Formula
C16H24N2O2
Molecular Weight
276.37
MDL Number
MFCD01321148
PubChem ID
3575823
Melting Point
77 - 81 °C (Lit.)
Appearance
White to off-white crystaline powder
Optical Rotation
[á]20/D = 6 ° (C = 1 in Chloroform)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(+)-1-Benzyl-3-(Boc-amino)pyrrolidine is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Peptide Synthesis: It is commonly used in solid-phase peptide synthesis, where its protective Boc group helps in the selective formation of peptide bonds, enhancing yield and purity.
  • Chiral Catalysis: The compound is valuable in asymmetric synthesis, acting as a chiral catalyst that improves the enantioselectivity of reactions, which is crucial in producing optically active compounds.
  • Research in Neuroscience: It is utilized in studies investigating the mechanisms of neurotransmission, aiding in the development of potential treatments for cognitive disorders.
  • Material Science: The compound finds applications in creating specialized polymers and materials, benefiting industries that require high-performance materials with specific chemical properties.

Citations