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Catalog Number:
41576
CAS Number:
114636-37-2
(S)-(-)-1-Boc-3-acetamidopyrrolidine
Purity:
≥ 97% (GC)
Synonym(s):
tert-Butyl(3S)-3-(acetylamino)-1-pyrrolidinecarboxylate
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Product Information

(S)-(-)-1-Boc-3-acetamidopyrrolidine is a versatile compound widely utilized in the pharmaceutical and chemical industries. This chiral building block is essential for the synthesis of various bioactive molecules, particularly in the development of pharmaceuticals targeting neurological disorders and other therapeutic areas. Its unique structure, featuring a tert-butyl carbamate protecting group, enhances its stability and reactivity, making it an ideal candidate for complex organic synthesis. Researchers appreciate its ability to facilitate the formation of intricate molecular architectures while maintaining high enantiomeric purity.

In addition to its applications in drug development, (S)-(-)-1-Boc-3-acetamidopyrrolidine serves as a valuable intermediate in the synthesis of peptide and heterocyclic compounds. Its compatibility with various coupling reactions allows for efficient incorporation into larger molecular frameworks, streamlining the synthesis process. This compound's favorable properties and practical applications make it an essential tool for chemists and researchers aiming to innovate in the fields of medicinal chemistry and organic synthesis.

Synonyms
tert-Butyl(3S)-3-(acetylamino)-1-pyrrolidinecarboxylate
CAS Number
114636-37-2
Purity
≥ 97% (GC)
Molecular Formula
C11H20N2O3
Molecular Weight
228.29
MDL Number
MFCD08704350
PubChem ID
14041207
Melting Point
86 - 90 °C
Appearance
White to tan solid
Optical Rotation
[á]20/D = -18 ° (C = 3.5 in methanol)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
tert-Butyl(3S)-3-(acetylamino)-1-pyrrolidinecarboxylate
CAS Number
114636-37-2
Purity
≥ 97% (GC)
Molecular Formula
C11H20N2O3
Molecular Weight
228.29
MDL Number
MFCD08704350
PubChem ID
14041207
Melting Point
86 - 90 °C
Appearance
White to tan solid
Optical Rotation
[á]20/D = -18 ° (C = 3.5 in methanol)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(-)-1-Boc-3-acetamidopyrrolidine is widely utilized in research focused on

  • Synthesis of Pharmaceuticals: This compound serves as a key intermediate in the synthesis of various pharmaceutical agents, particularly in the development of drugs targeting neurological disorders.
  • Peptide Synthesis: It is used in the preparation of peptide-based therapeutics, enhancing the stability and bioavailability of the resulting compounds.
  • Chiral Building Block: As a chiral building block, it plays a crucial role in asymmetric synthesis, allowing chemists to create compounds with specific stereochemistry, which is vital in drug design.
  • Research in Medicinal Chemistry: It is employed in medicinal chemistry research to explore new drug candidates, particularly those that require modification of amino acid structures.
  • Bioconjugation Techniques: The compound can be utilized in bioconjugation methods, facilitating the attachment of drugs to biomolecules, which can improve targeted delivery in therapeutic applications.

Citations