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Catalog Number:
41575
CAS Number:
550371-67-0
(R)-(+)-1-Boc-3-acetamidopyrrolidine
Purity:
≥ 97% (GC)
Synonym(s):
tert-Butyl(3R)-3-(acetylamino)-1-pyrrolidinecarboxylate
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Product Information

(R)-(+)-1-Boc-3-acetamidopyrrolidine is a versatile compound widely utilized in the field of organic synthesis and medicinal chemistry. This chiral building block is particularly valuable for researchers focusing on the development of pharmaceuticals, as it serves as an essential intermediate in the synthesis of various bioactive molecules. Its unique structure, featuring a tert-butyl carbamate protecting group, enhances its stability and reactivity, making it an ideal candidate for complex chemical transformations.

In addition to its applications in drug development, (R)-(+)-1-Boc-3-acetamidopyrrolidine is also employed in the synthesis of peptide-based therapeutics and other nitrogen-containing compounds. Its ability to facilitate the formation of stereocenters allows for the creation of compounds with specific biological activities, which is crucial in the design of targeted therapies. Researchers and industry professionals can benefit from its ease of use and compatibility with various reaction conditions, streamlining the synthesis process and improving yields in their projects.

Synonyms
tert-Butyl(3R)-3-(acetylamino)-1-pyrrolidinecarboxylate
CAS Number
550371-67-0
Purity
≥ 97% (GC)
Molecular Formula
C11H20N2O3
Molecular Weight
228.29
MDL Number
MFCD08276861
PubChem ID
14041207
Melting Point
85 - 89 °C
Appearance
White to off-white powder
Optical Rotation
[á]20/D = -17 ° (C = 3.5 in methanol)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
tert-Butyl(3R)-3-(acetylamino)-1-pyrrolidinecarboxylate
CAS Number
550371-67-0
Purity
≥ 97% (GC)
Molecular Formula
C11H20N2O3
Molecular Weight
228.29
MDL Number
MFCD08276861
PubChem ID
14041207
Melting Point
85 - 89 °C
Appearance
White to off-white powder
Optical Rotation
[á]20/D = -17 ° (C = 3.5 in methanol)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(+)-1-Boc-3-acetamidopyrrolidine is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of novel analgesics and anti-inflammatory drugs.
  • Peptide Synthesis: It is employed in the synthesis of peptides, enhancing the efficiency of coupling reactions due to its protective Boc (tert-butoxycarbonyl) group, which simplifies the purification process.
  • Chiral Building Blocks: As a chiral compound, it is used in asymmetric synthesis, allowing researchers to create enantiomerically pure substances that are crucial in drug development.
  • Neuroscience Research: This chemical is utilized in studies related to neurotransmitter modulation, aiding in the understanding of neurological disorders and the development of related therapies.
  • Material Science: It finds applications in the development of advanced materials, particularly in creating polymers with specific functionalities for biomedical applications.

Citations