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Catalog Number:
41574
CAS Number:
108963-96-8
Boc-Pyr-OMe
Purity:
≥ 97% (HPLC)
Synonym(s):
(S)-Methyl-N-Boc-pyroglutamate, N-Boc-(S)-2-pyrrolidone-5-carboxylic acid methyl ester, Boc-L-pyroglutamic acid methyl ester, N-Boc-5-oxo-L-proline methyl ester
Hazmat
Documents
$72.31 /1G
Pack Size Availability Price
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Product Information
Synonyms
(S)-Methyl-N-Boc-pyroglutamate, N-Boc-(S)-2-pyrrolidone-5-carboxylic acid methyl ester, Boc-L-pyroglutamic acid methyl ester, N-Boc-5-oxo-L-proline methyl ester
CAS Number
108963-96-8
Purity
≥ 97% (HPLC)
Molecular Formula
C11H17NO5
Molecular Weight
0
MDL Number
MFCD06809720
PubChem ID
4175931
Melting Point
68 - 72 °C
Appearance
White to tan crystalline powder
Optical Rotation
[á]22/D = -32 ° (C = 0.5 in Chloroform)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(S)-Methyl-N-Boc-pyroglutamate, N-Boc-(S)-2-pyrrolidone-5-carboxylic acid methyl ester, Boc-L-pyroglutamic acid methyl ester, N-Boc-5-oxo-L-proline methyl ester
CAS Number
108963-96-8
Purity
≥ 97% (HPLC)
Molecular Formula
C11H17NO5
Molecular Weight
0
MDL Number
MFCD06809720
PubChem ID
4175931
Melting Point
68 - 72 °C
Appearance
White to tan crystalline powder
Optical Rotation
[á]22/D = -32 ° (C = 0.5 in Chloroform)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-Pyr-OMe is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing chemists to selectively modify amino acids without affecting others. This is crucial for creating complex peptides used in pharmaceuticals.
  • Drug Development: Its role in drug design is significant, particularly in optimizing the pharmacokinetic properties of drug candidates. Researchers can enhance solubility and stability, leading to more effective medications.
  • Bioconjugation: Boc-Pyr-OMe is employed in bioconjugation processes, where it helps attach biomolecules to drugs or imaging agents. This application is vital in developing targeted therapies and diagnostic tools in medicine.
  • Organic Synthesis: The compound is a valuable intermediate in organic synthesis, aiding in the creation of various chemical entities. Its versatility allows chemists to explore new synthetic pathways efficiently.
  • Research in Medicinal Chemistry: It is used in medicinal chemistry research to explore new compounds with potential therapeutic effects, particularly in the development of novel antibiotics and anticancer agents.

Citations