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Catalog Number:
41557
CAS Number:
122536-77-0
(R)-3-(Boc-amino)pyrrolidine
Purity:
≥ 99%
Synonym(s):
tert-Butyl (R)-3-pyrrolidinylcarbamate
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Product Information

(R)-3-(Boc-amino)pyrrolidine is a versatile compound widely utilized in the field of organic synthesis and medicinal chemistry. This chiral pyrrolidine derivative, characterized by its tert-butyl carbamate protective group, serves as a crucial building block in the synthesis of various pharmaceuticals and bioactive molecules. Its unique structure allows for the introduction of amino functionalities, making it an essential intermediate in the development of peptide-based therapeutics and other complex organic compounds. Researchers appreciate its ability to enhance solubility and stability in formulations, which is vital for drug development processes.

In addition to its applications in pharmaceutical synthesis, (R)-3-(Boc-amino)pyrrolidine is also employed in the production of agrochemicals and fine chemicals. Its chiral nature allows for the creation of enantiomerically pure compounds, which is increasingly important in the development of effective and safe drugs. The compound's favorable reactivity profile and compatibility with various reaction conditions make it a preferred choice for chemists looking to streamline their synthetic routes. Overall, (R)-3-(Boc-amino)pyrrolidine stands out as a valuable asset in both research and industrial applications, offering significant advantages in efficiency and product quality.

Synonyms
tert-Butyl (R)-3-pyrrolidinylcarbamate
CAS Number
122536-77-0
Purity
≥ 99%
Molecular Formula
C9H18N2O2
Molecular Weight
186.25
MDL Number
MFCD00143191
PubChem ID
2757234
Melting Point
50 - 54 °C (Lit.)
Appearance
White to almost white crystals
Optical Rotation
[a]D20 = 21 - 23 ° (C=1 in MeOH)
Conditions
Store at RT
General Information
Synonyms
tert-Butyl (R)-3-pyrrolidinylcarbamate
CAS Number
122536-77-0
Purity
≥ 99%
Molecular Formula
C9H18N2O2
Molecular Weight
186.25
MDL Number
MFCD00143191
PubChem ID
2757234
Melting Point
50 - 54 °C (Lit.)
Appearance
White to almost white crystals
Optical Rotation
[a]D20 = 21 - 23 ° (C=1 in MeOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-3-(Boc-amino)pyrrolidine is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Peptide Synthesis: It is commonly used in the synthesis of peptides, where its protective Boc group allows for selective reactions, enhancing the efficiency of peptide assembly.
  • Chiral Building Blocks: As a chiral compound, it plays a crucial role in asymmetric synthesis, providing researchers with a means to create enantiomerically pure substances, which are vital in drug formulation.
  • Research in Organic Chemistry: It is employed in various organic synthesis reactions, aiding chemists in exploring new reaction pathways and developing innovative synthetic methodologies.
  • Bioconjugation Applications: The compound's functional groups allow for bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other compounds, which is essential in biomedical research and diagnostics.

Citations