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Catalog Number:
41525
CAS Number:
68108-18-9
(S)-(-)-4-Hydroxy-2-pyrrolidinone
Purity:
≥ 96.5% (GC)
Synonym(s):
(S)-β-Hydroxy-γ-butyrolactam
Documents
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Product Information

(S)-(-)-4-Hydroxy-2-pyrrolidinone is a versatile compound known for its unique properties and applications in various fields, particularly in pharmaceuticals and organic synthesis. This chiral building block is essential in the synthesis of various bioactive molecules, making it invaluable for researchers and industry professionals focused on drug development. Its ability to act as a precursor in the synthesis of amino acids and other nitrogen-containing compounds enhances its utility in medicinal chemistry. Additionally, (S)-(-)-4-Hydroxy-2-pyrrolidinone is recognized for its role in the production of chiral ligands, which are crucial in asymmetric synthesis processes, allowing for the creation of compounds with specific stereochemistry.

The compound's stability and reactivity make it an ideal candidate for various applications, including the development of novel therapeutic agents and the formulation of advanced materials. Its unique hydroxyl and carbonyl functional groups facilitate diverse chemical reactions, enabling the creation of complex molecular architectures. Researchers can leverage (S)-(-)-4-Hydroxy-2-pyrrolidinone to enhance the efficacy and specificity of their compounds, ultimately leading to improved outcomes in drug discovery and development.

Synonyms
(S)-β-Hydroxy-γ-butyrolactam
CAS Number
68108-18-9
Purity
≥ 96.5% (GC)
Molecular Formula
C4H7NO2
Molecular Weight
101.1
MDL Number
MFCD00273370
PubChem ID
152807
Melting Point
156 - 159 °C (Lit.)
Appearance
White to off-white solid
Optical Rotation
[á]23/D = 43 ° (C = 1 in ethanol)
Conditions
Store at RT
General Information
Synonyms
(S)-β-Hydroxy-γ-butyrolactam
CAS Number
68108-18-9
Purity
≥ 96.5% (GC)
Molecular Formula
C4H7NO2
Molecular Weight
101.1
MDL Number
MFCD00273370
PubChem ID
152807
Melting Point
156 - 159 °C (Lit.)
Appearance
White to off-white solid
Optical Rotation
[á]23/D = 43 ° (C = 1 in ethanol)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(-)-4-Hydroxy-2-pyrrolidinone is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting central nervous system disorders.
  • Chiral Catalysis: It is used as a chiral ligand in asymmetric synthesis, providing researchers with a means to produce enantiomerically pure compounds, which are crucial in drug formulation.
  • Biochemical Research: The compound is employed in studies related to neurotransmitter modulation, helping scientists understand its effects on brain chemistry and potential therapeutic applications.
  • Polymer Chemistry: It can be used to create biocompatible polymers, making it valuable in the development of drug delivery systems and medical devices.
  • Cosmetic Formulations: Due to its hydrophilic properties, it is incorporated into skincare products to enhance moisture retention and improve skin texture.

Citations