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Catalog Number:
41503
CAS Number:
1212176-33-4
(R)-1-Boc-4-oxopiperidine-2-carboxylic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
(2R)-1-Boc-4-oxopipecolic acid
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Product Information

(R)-1-Boc-4-oxopiperidine-2-carboxylic acid is a versatile compound widely utilized in the field of organic synthesis and medicinal chemistry. This chiral building block is particularly valuable for the development of pharmaceuticals, as it can serve as an intermediate in the synthesis of various bioactive molecules. Its unique structure, featuring a piperidine ring and a Boc (tert-butyloxycarbonyl) protecting group, enhances its stability and reactivity, making it an ideal candidate for complex organic transformations. Researchers appreciate its role in the synthesis of peptide-like compounds and its potential applications in drug discovery, particularly in the development of novel therapeutics targeting central nervous system disorders.

The compound's ability to facilitate the introduction of functional groups while maintaining stereochemical integrity is a notable advantage over similar compounds. This characteristic allows for greater flexibility in designing molecules with specific biological activities. Additionally, (R)-1-Boc-4-oxopiperidine-2-carboxylic acid is recognized for its compatibility with various reaction conditions, making it a reliable choice for both academic and industrial applications. Its relevance in the synthesis of chiral intermediates positions it as a key player in advancing pharmaceutical research and development.

Synonyms
(2R)-1-Boc-4-oxopipecolic acid
CAS Number
1212176-33-4
Purity
95 - 105% (Assay by titration)
Molecular Formula
C11H17NO5
Molecular Weight
243.26
MDL Number
MFCD09953681
PubChem ID
46835694
Melting Point
119 - 124 °C
Appearance
White to off-white solid
Optical Rotation
[á]22/D = 22.0 ° (C = 1 in Chloroform)
Conditions
Store at RT
General Information
Synonyms
(2R)-1-Boc-4-oxopipecolic acid
CAS Number
1212176-33-4
Purity
95 - 105% (Assay by titration)
Molecular Formula
C11H17NO5
Molecular Weight
243.26
MDL Number
MFCD09953681
PubChem ID
46835694
Melting Point
119 - 124 °C
Appearance
White to off-white solid
Optical Rotation
[á]22/D = 22.0 ° (C = 1 in Chloroform)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-1-Boc-4-oxopiperidine-2-carboxylic acid is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of analgesics and anti-inflammatory drugs.
  • Peptide Synthesis: It is used in the preparation of peptide-based therapeutics, offering a stable and versatile building block for researchers in medicinal chemistry.
  • Biochemical Research: The compound aids in the study of enzyme inhibitors and receptor interactions, providing insights that can lead to new drug discoveries.
  • Material Science: Its properties make it suitable for creating specialized polymers and materials, which can be used in coatings and drug delivery systems.
  • Organic Synthesis: This chemical is a valuable reagent in organic synthesis, allowing chemists to create complex molecular structures efficiently.

Citations