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Catalog Number:
41320
CAS Number:
55511-44-9
R-(+)-Aminoglutethimide
Purity:
≥ 97% (Assay)
Synonym(s):
(R-3-(4-Aminophenyl)-3-ethylpiperidine-2,6-dione, (3R-3-Amino-4-ethyl-4-phenylpiperidine-2,6-dione
Documents
$217.63 /500MG
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Product Information

(R)-(+)-Aminoglutethimide is a chiral compound recognized for its significant role in pharmaceutical applications, particularly in the treatment of hormone-dependent conditions. This compound acts as an aromatase inhibitor, making it valuable in the management of breast cancer by reducing estrogen production. Its unique structure allows it to selectively target specific pathways, providing a therapeutic advantage over non-selective agents. Researchers have also explored its potential in treating Cushing's syndrome due to its ability to inhibit steroidogenesis, showcasing its versatility in endocrine disorders.

In addition to its therapeutic applications, (R)-(+)-Aminoglutethimide is utilized in various research settings, particularly in studies focused on hormone regulation and cancer biology. Its effectiveness in modulating hormonal pathways makes it a critical tool for scientists investigating the mechanisms of hormone-related diseases. The compound's stability and solubility further enhance its usability in laboratory settings, ensuring reliable results in experimental applications. Overall, (R)-(+)-Aminoglutethimide stands out for its targeted action and broad applicability in both clinical and research environments.

Synonyms
(R-3-(4-Aminophenyl)-3-ethylpiperidine-2,6-dione, (3R-3-Amino-4-ethyl-4-phenylpiperidine-2,6-dione
CAS Number
55511-44-9
Purity
≥ 97% (Assay)
Molecular Formula
C13H16N2O2
Molecular Weight
232.28
MDL Number
MFCD03094025
PubChem ID
2145
Melting Point
115.5 - 119.5 °C (Lit.)
Optical Rotation
[α]20D = 160 ± 1 ° (C = 1 in MeOH)
Conditions
Store at RT
General Information
Synonyms
(R-3-(4-Aminophenyl)-3-ethylpiperidine-2,6-dione, (3R-3-Amino-4-ethyl-4-phenylpiperidine-2,6-dione
CAS Number
55511-44-9
Purity
≥ 97% (Assay)
Molecular Formula
C13H16N2O2
Molecular Weight
232.28
MDL Number
MFCD03094025
PubChem ID
2145
Melting Point
115.5 - 119.5 °C (Lit.)
Optical Rotation
[α]20D = 160 ± 1 ° (C = 1 in MeOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(+)-Aminoglutethimide is widely utilized in research focused on

  • Pharmaceutical Development: This compound is primarily used in the synthesis of steroid hormone inhibitors, making it valuable in developing medications for conditions like Cushing's syndrome.
  • Cancer Research: It has applications in oncology, particularly in studying its effects on adrenal cancer and breast cancer, providing insights into hormone-related tumor growth.
  • Endocrine Studies: Researchers employ this compound to investigate the regulation of steroidogenesis, enhancing understanding of hormonal balance and its implications for various diseases.
  • Drug Interaction Studies: This chemical is used to explore interactions with other drugs, helping to identify potential side effects and improve therapeutic strategies.
  • Biochemical Research: It serves as a tool in biochemical assays to study enzyme activities related to steroid metabolism, contributing to advancements in metabolic disorder treatments.

Citations