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Catalog Number:
41314
CAS Number:
97070-79-6
(R)-(+)-4-Chloromandelonitrile
Purity:
≥ 97% (Assay)
Synonym(s):
(2R)-2-(4-chlorophenyl)-2-hydroxyacetonitrile
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Product Information

(R)-(+)-4-Chloromandelonitrile is a versatile compound recognized for its significant role in organic synthesis and pharmaceutical applications. This chiral nitrile features a unique 4-chlorophenyl group, making it an essential building block in the development of various agrochemicals and pharmaceuticals. Its ability to act as a chiral auxiliary allows researchers to create enantiomerically pure compounds, which is crucial in the synthesis of active pharmaceutical ingredients (APIs). The compound's properties facilitate its use in asymmetric synthesis, enabling the production of high-value chiral molecules with enhanced efficacy and reduced side effects.

In addition to its applications in the pharmaceutical industry, (R)-(+)-4-Chloromandelonitrile is also utilized in the development of fine chemicals and specialty materials. Its stability and reactivity make it an ideal candidate for various chemical transformations, including nucleophilic substitutions and condensation reactions. Researchers and industry professionals can leverage this compound to streamline their synthesis processes, improve yields, and enhance the overall efficiency of their projects.

Synonyms
(2R)-2-(4-chlorophenyl)-2-hydroxyacetonitrile
CAS Number
97070-79-6
Purity
≥ 97% (Assay)
Molecular Formula
C8H6ClNO
Molecular Weight
167.59
MDL Number
MFCD01321260
PubChem ID
4401784
Melting Point
70 - 74 °C (Lit.)
Optical Rotation
[α]20D = 39 ± 1 ° (C = 1 in CHCl3)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(2R)-2-(4-chlorophenyl)-2-hydroxyacetonitrile
CAS Number
97070-79-6
Purity
≥ 97% (Assay)
Molecular Formula
C8H6ClNO
Molecular Weight
167.59
MDL Number
MFCD01321260
PubChem ID
4401784
Melting Point
70 - 74 °C (Lit.)
Optical Rotation
[α]20D = 39 ± 1 ° (C = 1 in CHCl3)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(+)-4-Chloromandelonitrile is widely utilized in research focused on

  • Synthesis of Pharmaceuticals: This compound serves as an important intermediate in the synthesis of various pharmaceutical agents, particularly in the development of anti-inflammatory and analgesic drugs.
  • Agricultural Chemicals: It is used in the formulation of agrochemicals, contributing to the creation of effective pesticides and herbicides that help in crop protection.
  • Organic Synthesis: Researchers leverage its unique chemical properties to create complex organic molecules, making it valuable in academic and industrial laboratories for developing new materials.
  • Chiral Catalysis: Its chirality allows it to be used in asymmetric synthesis, providing advantages in producing enantiomerically pure compounds, which are crucial in the pharmaceutical industry.
  • Analytical Chemistry: This compound is utilized as a standard in analytical methods, aiding in the detection and quantification of similar compounds in various samples.

Citations