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Catalog Number:
05137
CAS Number:
101555-63-9
Fmoc-D-homoproline
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-HomoPro-OH, Fmoc-D-pipecolic acid
Documents
$39.26 /1G
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Product Information

Fmoc-D-homoproline is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound, characterized by its unique fluorenylmethoxycarbonyl (Fmoc) protecting group, enhances the stability and solubility of peptides, making it an essential building block in the synthesis of complex peptides and proteins. Its structure allows for efficient coupling reactions, facilitating the creation of diverse peptide sequences that are crucial in pharmaceutical research and development. Researchers appreciate Fmoc-D-homoproline for its ability to improve the yield and purity of synthesized peptides, which is vital for applications in drug discovery and therapeutic development.

In addition to its role in peptide synthesis, Fmoc-D-homoproline is also valuable in the study of protein folding and structure-function relationships. Its incorporation into peptides can help mimic natural biological processes, providing insights into enzyme activity and receptor interactions. This compound stands out among similar products due to its ease of use and compatibility with various coupling reagents, making it a preferred choice for professionals in the fields of biochemistry and medicinal chemistry.

Synonyms
Fmoc-D-HomoPro-OH, Fmoc-D-pipecolic acid
CAS Number
101555-63-9
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD00235899
PubChem ID
3790985
Appearance
White powder
Optical Rotation
[a]D20 = +22 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-HomoPro-OH, Fmoc-D-pipecolic acid
CAS Number
101555-63-9
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD00235899
PubChem ID
3790985
Appearance
White powder
Optical Rotation
[a]D20 = +22 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-homoproline is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create specific sequences for various applications in drug development.
  • Drug Discovery: Fmoc-D-homoproline is used in the design of novel therapeutics, particularly in the development of inhibitors that target specific proteins, enhancing the efficiency of drug discovery processes.
  • Bioconjugation: It plays a crucial role in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Neuroscience: This compound is utilized in studies related to neuropeptides, helping researchers understand neurological pathways and potential treatments for neurological disorders.
  • Protein Engineering: Fmoc-D-homoproline is beneficial in protein engineering, where it aids in the modification of proteins to improve their stability and functionality for various industrial applications.

Citations