Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
37545
CAS Number:
29739-88-6
N-(p-Toluenesulfonyl)-L-phenylalanyl chloride [Optical Resolving Reagent for Alcohols]
Purity:
≥ 97% (T)
Synonym(s):
Tosyl-L-phenylalanyl chloride
Hazmat
Documents
$51.18 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

N-(p-Toluenesulfonyl)-L-phenylalanyl chloride is a versatile reagent widely utilized in organic synthesis, particularly as an optical resolving agent for alcohols. This compound is recognized for its ability to facilitate the separation of enantiomers, making it invaluable in the pharmaceutical and agrochemical industries where chirality plays a crucial role in the efficacy and safety of active ingredients. Its unique sulfonyl group enhances reactivity, allowing for efficient transformations and the formation of stable intermediates.

Researchers and industry professionals appreciate N-(p-Toluenesulfonyl)-L-phenylalanyl chloride for its effectiveness in asymmetric synthesis, enabling the production of high-purity chiral compounds. This reagent is particularly beneficial in the development of new drugs, where the correct stereochemistry can significantly influence biological activity. Its application extends to the synthesis of various complex molecules, making it a key component in the toolkit of chemists focused on innovative solutions in drug discovery and development.

Synonyms
Tosyl-L-phenylalanyl chloride
CAS Number
29739-88-6
Purity
≥ 97% (T)
Molecular Formula
C16H16ClNO3S
Molecular Weight
337.82
MDL Number
MFCD00191583
PubChem ID
4093506
Melting Point
132 ?C (dec.)
Appearance
White to Orange to Green powder to crysta
Optical Rotation
[α]20D = 9 - 10 ° (C=3, CHCl3
Conditions
Store at RT
General Information
Synonyms
Tosyl-L-phenylalanyl chloride
CAS Number
29739-88-6
Purity
≥ 97% (T)
Molecular Formula
C16H16ClNO3S
Molecular Weight
337.82
MDL Number
MFCD00191583
PubChem ID
4093506
Melting Point
132 ?C (dec.)
Appearance
White to Orange to Green powder to crysta
Optical Rotation
[α]20D = 9 - 10 ° (C=3, CHCl3
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-(p-Toluenesulfonyl)-L-phenylalanyl chloride is widely utilized in research focused on:

  • Chiral Resolution: This compound serves as an effective resolving agent for alcohols, allowing chemists to separate enantiomers in asymmetric synthesis, which is crucial in pharmaceuticals for developing specific drug formulations.
  • Peptide Synthesis: It plays a significant role in peptide coupling reactions, enhancing the efficiency of synthesizing complex peptides used in drug development and biotechnology.
  • Analytical Chemistry: Researchers employ this compound in chromatography to improve the separation of chiral compounds, aiding in the analysis of drug purity and composition.
  • Biotechnology: Its application in modifying biomolecules helps in the design of targeted therapies, particularly in cancer treatment, by enabling the selective delivery of drugs to specific cells.
  • Material Science: The compound is also utilized in the development of novel materials with tailored properties, such as smart polymers that respond to environmental stimuli.

Citations