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Catalog Number:
37519
CAS Number:
39262-22-1
1R-(-)-10-Camphorsulfonyl chloride
Purity:
≥ 98% (T)
Synonym(s):
(-)-10-Camphorsulfonyl chloride
Hazmat
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Product Information

(1R)-(-)-10-Camphorsulfonyl chloride is a versatile reagent widely utilized in organic synthesis, particularly in the field of medicinal chemistry. This compound serves as an effective electrophilic sulfonylating agent, enabling the introduction of sulfonyl groups into various organic substrates. Its unique bicyclic structure enhances its reactivity, making it a valuable tool for researchers aiming to develop novel pharmaceuticals and agrochemicals. The compound is particularly favored for its ability to facilitate the formation of sulfonamides, which are critical in the synthesis of biologically active molecules.

In addition to its applications in drug discovery, (1R)-(-)-10-Camphorsulfonyl chloride is also employed in the preparation of chiral sulfonamides, which are essential for asymmetric synthesis. Its high selectivity and efficiency in reactions make it a preferred choice among chemists seeking to optimize their synthetic pathways. With its proven track record in enhancing reaction outcomes, this compound stands out as a key reagent for researchers and industry professionals focused on advancing chemical synthesis.

Synonyms
(-)-10-Camphorsulfonyl chloride
CAS Number
39262-22-1
Purity
≥ 98% (T)
Molecular Formula
C10H15ClO3S
Molecular Weight
250.74
MDL Number
MFCD00064155
PubChem ID
265799
Melting Point
66 - 68 ?C
Appearance
White to Almost white powder to crystal
Optical Rotation
[α]20D = -26 to -33 ° (C=1, CHCl3
Conditions
Store at RT
General Information
Synonyms
(-)-10-Camphorsulfonyl chloride
CAS Number
39262-22-1
Purity
≥ 98% (T)
Molecular Formula
C10H15ClO3S
Molecular Weight
250.74
MDL Number
MFCD00064155
PubChem ID
265799
Melting Point
66 - 68 ?C
Appearance
White to Almost white powder to crystal
Optical Rotation
[α]20D = -26 to -33 ° (C=1, CHCl3
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(1R)-(-)-10-Camphorsulfonyl chloride is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile reagent in organic chemistry, particularly in the synthesis of sulfonamides and other functionalized compounds, enhancing the efficiency of chemical reactions.
  • Pharmaceutical Development: It plays a crucial role in the pharmaceutical industry for the development of new drugs, particularly in the modification of active pharmaceutical ingredients (APIs) to improve their efficacy and stability.
  • Chiral Auxiliary: Its use as a chiral auxiliary in asymmetric synthesis allows researchers to produce enantiomerically pure compounds, which is vital in the production of many pharmaceuticals.
  • Polymer Chemistry: The compound is applied in the modification of polymers, improving their properties for specific applications, such as enhancing thermal stability and chemical resistance.
  • Analytical Chemistry: It is utilized in the development of analytical methods, aiding in the detection and quantification of various substances, which is essential for quality control in manufacturing processes.

Citations