Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
37504
CAS Number:
20445-33-4
(S-(+)-ॅ-Methoxy-ॅ-(trifluoromethyl)phenylacetyl chloride [for Determination of the optical purity of Alcohols and Amines]
Purity:
≥ 99% (GC)(T)
Synonym(s):
(S-(+)-MTPA-Cl, Mosher's acid chloride
Hazmat
Documents
$80.62 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

(S)-(+)-a-Methoxy-a-(trifluoromethyl)phenylacetyl chloride is a specialized chemical compound known for its utility in the determination of optical purity in various organic synthesis applications. This compound features a trifluoromethyl group, which enhances its reactivity and selectivity in chemical reactions, making it an invaluable tool for researchers and industry professionals focused on chiral synthesis and analysis. Its unique structure allows for precise manipulation in asymmetric synthesis, particularly in the pharmaceutical and agrochemical sectors, where the optical purity of compounds is critical for efficacy and safety.

The compound is particularly beneficial in the development of chiral intermediates and active pharmaceutical ingredients (APIs), where maintaining the desired stereochemistry is essential. Its application extends to the synthesis of complex molecules, enabling chemists to achieve high yields with minimal by-products. Additionally, the trifluoromethyl group contributes to improved solubility and stability, making it easier to handle in laboratory settings. Overall, (S)-(+)-a-Methoxy-a-(trifluoromethyl)phenylacetyl chloride stands out as a versatile reagent for advancing research and development in various chemical fields.

Synonyms
(S-(+)-MTPA-Cl, Mosher's acid chloride
CAS Number
20445-33-4
Purity
≥ 99% (GC)(T)
Molecular Formula
C10H8ClF3O2
Molecular Weight
252.62
MDL Number
MFCD00067105
PubChem ID
604961
Density
1.35
Appearance
Colorless to Almost colorless clear liqui
Boiling Point
99 °C / 12 mmHg
Refractive Index
1.47
Optical Rotation
149 ± 2 ° (C=2,Toluene)
Conditions
Store at 0 - 10 °C
General Information
Synonyms
(S-(+)-MTPA-Cl, Mosher's acid chloride
CAS Number
20445-33-4
Purity
≥ 99% (GC)(T)
Molecular Formula
C10H8ClF3O2
Molecular Weight
252.62
MDL Number
MFCD00067105
PubChem ID
604961
Density
1.35
Appearance
Colorless to Almost colorless clear liqui
Boiling Point
99 °C / 12 mmHg
Refractive Index
1.47
Optical Rotation
149 ± 2 ° (C=2,Toluene)
Conditions
Store at 0 - 10 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(+)-a-Methoxy-a-(trifluoromethyl)phenylacetyl chloride is widely utilized in research focused on:

  • Synthesis of Chiral Compounds: This chemical plays a crucial role in the synthesis of chiral intermediates, which are essential in the production of pharmaceuticals, ensuring the desired optical activity in drug formulations.
  • Pharmaceutical Development: It is used in the development of new drugs, particularly in the creation of compounds with specific stereochemistry, enhancing the efficacy and safety profiles of medications.
  • Analytical Chemistry: Researchers utilize this compound for determining the optical purity of various substances, which is vital in quality control processes in the pharmaceutical industry.
  • Fluorinated Compounds: The trifluoromethyl group provides unique properties, making it valuable in creating fluorinated compounds that exhibit improved biological activity and stability.
  • Material Science: This chemical is also explored in the development of advanced materials, where its unique chemical properties can lead to innovative applications in coatings and polymers.

Citations