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Catalog Number:
41432
CAS Number:
137848-29-4
S-(-)-2-Amino-2'-hydroxy-1,1'-binaphthyl
Purity:
≥ 98% (Chiral purity)
Synonym(s):
(S-(-)-1-(2-Amino-1-naphthyl)-2-naphthol, (S-(-)-NOBIN, (S-(-)-2'-Amino-1,1'-binaphthalen-2-ol
Hazmat
Documents
$177.67 /100MG
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Product Information

(S)-(-)-2-Amino-2'-hydroxy-1,1'-binaphthyl is a versatile chiral compound widely recognized for its applications in asymmetric synthesis and catalysis. This compound, also known as (S)-(-)-BINOL-amine, serves as a crucial building block in the development of various pharmaceuticals and agrochemicals. Its unique structural properties enable it to act as an effective ligand in transition metal-catalyzed reactions, facilitating the formation of enantiomerically enriched products. Researchers and industry professionals utilize this compound to enhance reaction selectivity and efficiency, making it invaluable in the synthesis of complex organic molecules.

In addition to its role in catalysis, (S)-(-)-2-Amino-2'-hydroxy-1,1'-binaphthyl is also employed in the development of chiral stationary phases for high-performance liquid chromatography (HPLC). This application is particularly beneficial for the separation and analysis of enantiomers in pharmaceutical research, ensuring the purity and efficacy of drug compounds. With its exceptional chiral properties and broad applicability, this compound stands out as a key resource for advancing research and development in various chemical industries.

Synonyms
(S-(-)-1-(2-Amino-1-naphthyl)-2-naphthol, (S-(-)-NOBIN, (S-(-)-2'-Amino-1,1'-binaphthalen-2-ol
CAS Number
137848-29-4
Purity
≥ 98% (Chiral purity)
Molecular Formula
C20H15NO
Molecular Weight
0
MDL Number
MFCD01882346
PubChem ID
3617797
Melting Point
171 - 175 °C
Appearance
White to light red to green powder
Optical Rotation
[α]20D = -121 ° (C = 1 in THF)
Conditions
Store at RT
General Information
Synonyms
(S-(-)-1-(2-Amino-1-naphthyl)-2-naphthol, (S-(-)-NOBIN, (S-(-)-2'-Amino-1,1'-binaphthalen-2-ol
CAS Number
137848-29-4
Purity
≥ 98% (Chiral purity)
Molecular Formula
C20H15NO
Molecular Weight
0
MDL Number
MFCD01882346
PubChem ID
3617797
Melting Point
171 - 175 °C
Appearance
White to light red to green powder
Optical Rotation
[α]20D = -121 ° (C = 1 in THF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(-)-2-Amino-2'-hydroxy-1,1'-binaphthyl is widely utilized in research focused on:

  • Asymmetric Synthesis: This compound serves as a chiral ligand in asymmetric catalysis, helping researchers create specific enantiomers in pharmaceuticals, which is crucial for drug efficacy and safety.
  • Organic Electronics: It is used in the development of organic light-emitting diodes (OLEDs), enhancing the performance and efficiency of display technologies in consumer electronics.
  • Biochemical Research: The compound acts as a building block in the synthesis of various biologically active molecules, aiding in the discovery of new therapeutic agents in medicinal chemistry.
  • Environmental Chemistry: It is applied in the study of chiral pollutants, helping researchers understand the environmental impact of various chemicals and their degradation pathways.
  • Material Science: The compound is utilized in the formulation of advanced materials, such as sensors and catalysts, offering improved performance compared to traditional materials.

Citations