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Catalog Number:
41046
CAS Number:
1264520-63-9
O-TBDPS-D-Thr-N-Boc-L-tert-Leu-Diphenylphosphine
Purity:
≥ 98% (HPLC)
Synonym(s):
N-(tert-Butoxycarbonyl)-L-tert-leucineN-[(2R,3S)-3-(tert-Butyldiphenylsilyloxy)-1-(diphenylphosphino)-2-butyl]amide, N-Boc-L-tert-leucineN-[(2R,3S)-3-(tert-butyldiphenylsilyloxy)-1-(diphenylphosphino)-2-butyl]amide
Documents
$550.00 /100MG
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Product Information

O-TBDPS-D-Thr-N-Boc-L-tert-Leu-Diphenylphosphine is a sophisticated compound widely utilized in the field of organic synthesis and medicinal chemistry. This compound, recognized for its unique structure, serves as a valuable building block in the development of complex molecules, particularly in the synthesis of peptide-based therapeutics. Its ability to protect functional groups while facilitating selective reactions makes it an essential tool for researchers aiming to create intricate molecular architectures.

The compound's diphenylphosphine moiety enhances its reactivity, allowing for efficient coupling reactions, which are crucial in the formation of peptide bonds. Additionally, the tert-butyl and Boc protecting groups provide stability and ease of handling, making it suitable for various synthetic pathways. Researchers and industry professionals can leverage O-TBDPS-D-Thr-N-Boc-L-tert-Leu-Diphenylphosphine in drug discovery, particularly in the design of inhibitors and other bioactive compounds, showcasing its potential in advancing pharmaceutical development.

Synonyms
N-(tert-Butoxycarbonyl)-L-tert-leucineN-[(2R,3S)-3-(tert-Butyldiphenylsilyloxy)-1-(diphenylphosphino)-2-butyl]amide, N-Boc-L-tert-leucineN-[(2R,3S)-3-(tert-butyldiphenylsilyloxy)-1-(diphenylphosphino)-2-butyl]amide
CAS Number
1264520-63-9
Purity
≥ 98% (HPLC)
Molecular Formula
C43H57N2O4PSi
Molecular Weight
725.0
MDL Number
MFCD27976839
PubChem ID
76447053
Melting Point
56 °C (Lit.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -29 to -26 ° (C = 1 in CHCl3)
Conditions
Store at RT
General Information
Synonyms
N-(tert-Butoxycarbonyl)-L-tert-leucineN-[(2R,3S)-3-(tert-Butyldiphenylsilyloxy)-1-(diphenylphosphino)-2-butyl]amide, N-Boc-L-tert-leucineN-[(2R,3S)-3-(tert-butyldiphenylsilyloxy)-1-(diphenylphosphino)-2-butyl]amide
CAS Number
1264520-63-9
Purity
≥ 98% (HPLC)
Molecular Formula
C43H57N2O4PSi
Molecular Weight
725.0
MDL Number
MFCD27976839
PubChem ID
76447053
Melting Point
56 °C (Lit.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -29 to -26 ° (C = 1 in CHCl3)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

O-TBDPS-D-Thr-N-Boc-L-tert-Leu-Diphenylphosphine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is instrumental in the synthesis of peptides, particularly in protecting the amino acid side chains during chemical reactions. Its stability and effectiveness make it a preferred choice among chemists.
  • Drug Development: It plays a crucial role in the pharmaceutical industry, aiding in the design and synthesis of new drug candidates by facilitating the formation of complex molecular structures.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to other entities, enhancing the specificity and efficacy of therapeutic agents.
  • Organic Synthesis: It serves as a versatile building block in organic synthesis, allowing researchers to create a variety of compounds with desired properties, streamlining the development of new materials.
  • Research in Catalysis: This chemical is also applied in catalytic processes, where it aids in accelerating chemical reactions, making it valuable for researchers looking to improve reaction efficiencies.

Citations