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Catalog Number:
41556
CAS Number:
320343-60-0
(R)-1-Boc-4-hydroxy-2-pyrrolidinone
Purity:
≥ 97%
Synonym(s):
tert-Butyl(R)-4-hydroxy-2-oxopyrrolidine-1-carboxylate
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Product Information

(R)-1-Boc-4-hydroxy-2-pyrrolidinone is a versatile compound widely utilized in the pharmaceutical and chemical industries. This chiral building block is essential for synthesizing various biologically active molecules, particularly in the development of pharmaceutical intermediates. Its unique structure allows for the introduction of hydroxyl and carbonyl functionalities, making it an ideal candidate for applications in asymmetric synthesis and drug discovery. Researchers appreciate its role in the preparation of complex molecules, including potential therapeutic agents targeting neurological disorders and other medical conditions.

The compound's stability and ease of handling further enhance its appeal, allowing for efficient processing in laboratory settings. Additionally, (R)-1-Boc-4-hydroxy-2-pyrrolidinone can be employed in the synthesis of peptide-based drugs, providing a strategic advantage in medicinal chemistry. Its ability to facilitate the formation of diverse molecular architectures positions it as a valuable tool for chemists aiming to innovate and optimize drug formulations. With its proven track record in research and development, this compound is a must-have for professionals seeking to advance their projects in the pharmaceutical landscape.

Synonyms
tert-Butyl(R)-4-hydroxy-2-oxopyrrolidine-1-carboxylate
CAS Number
320343-60-0
Purity
≥ 97%
Molecular Formula
C9H15NO4
Molecular Weight
201.22
MDL Number
MFCD08561116
PubChem ID
9899129
Melting Point
136 - 141 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[á]22/D = -28 ° (C = 0.5 in Chloroform)
Conditions
Store at RT
General Information
Synonyms
tert-Butyl(R)-4-hydroxy-2-oxopyrrolidine-1-carboxylate
CAS Number
320343-60-0
Purity
≥ 97%
Molecular Formula
C9H15NO4
Molecular Weight
201.22
MDL Number
MFCD08561116
PubChem ID
9899129
Melting Point
136 - 141 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[á]22/D = -28 ° (C = 0.5 in Chloroform)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-1-Boc-4-hydroxy-2-pyrrolidinone is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders, enhancing therapeutic efficacy.
  • Peptide Synthesis: It is used in the formation of peptide bonds, making it valuable in the production of peptide-based drugs and biologics, which are crucial in modern medicine.
  • Chiral Building Blocks: As a chiral compound, it plays a significant role in asymmetric synthesis, allowing chemists to create specific enantiomers that are often more effective in biological applications.
  • Research in Organic Chemistry: This compound is a useful reagent in various organic reactions, aiding researchers in exploring new synthetic pathways and methodologies.
  • Material Science: It finds applications in the development of polymers and materials with specific properties, contributing to advancements in coatings, adhesives, and other industrial products.

Citations