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Catalog Number:
41341
CAS Number:
10606-72-1
Ethyl (R)-(-)-mandelate
Purity:
≥ 98.5% (Chiral purity)
Synonym(s):
Ethyl D-(-)-Mandelate, D-(-)-Mandelic acid ethyl ester
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Product Information

Ethyl (R)-(-)-mandelate is a versatile compound widely recognized for its applications in the synthesis of pharmaceuticals and fine chemicals. This chiral ester is particularly valued in asymmetric synthesis, where it serves as a key intermediate in the production of various bioactive molecules. Its unique optical properties make it an essential reagent in the development of chiral drugs, enhancing the efficacy and specificity of therapeutic agents. Researchers and industry professionals utilize Ethyl (R)-(-)-mandelate in the formulation of anti-inflammatory and analgesic medications, as well as in the synthesis of flavoring agents and fragrances, capitalizing on its pleasant aromatic profile.

In addition to its pharmaceutical applications, Ethyl (R)-(-)-mandelate is also employed in the production of agrochemicals and as a chiral auxiliary in organic synthesis. Its ability to facilitate enantioselective reactions positions it as a valuable tool for chemists aiming to create compounds with desired stereochemistry. The compound's favorable safety profile and ease of handling further enhance its appeal in laboratory and industrial settings, making it an indispensable resource for those engaged in cutting-edge research and development.

Synonyms
Ethyl D-(-)-Mandelate, D-(-)-Mandelic acid ethyl ester
CAS Number
10606-72-1
Purity
≥ 98.5% (Chiral purity)
Molecular Formula
C10H12O3
Molecular Weight
180.2
MDL Number
MFCD00064248
PubChem ID
13050
Melting Point
33 - 34 °C (Lit.)
Appearance
White solid, powder or crystals
Boiling Point
103 - 105 °C / 2 mmHg (Lit.)
Optical Rotation
[α]20D = -137 to -133 ° (C = 3 in CHCl3)
Conditions
Store at RT
General Information
Synonyms
Ethyl D-(-)-Mandelate, D-(-)-Mandelic acid ethyl ester
CAS Number
10606-72-1
Purity
≥ 98.5% (Chiral purity)
Molecular Formula
C10H12O3
Molecular Weight
180.2
MDL Number
MFCD00064248
PubChem ID
13050
Melting Point
33 - 34 °C (Lit.)
Appearance
White solid, powder or crystals
Boiling Point
103 - 105 °C / 2 mmHg (Lit.)
Optical Rotation
[α]20D = -137 to -133 ° (C = 3 in CHCl3)
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ethyl (R)-(-)-mandelate is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a chiral building block in the synthesis of various pharmaceuticals, enhancing the efficacy and specificity of drug formulations.
  • Flavor and Fragrance Industry: It is used as a flavoring agent due to its pleasant aroma, making it popular in food and cosmetic products.
  • Chiral Resolution: Ethyl (R)-(-)-mandelate is effective in the chiral resolution of racemic mixtures, helping chemists separate enantiomers for more targeted applications.
  • Research in Organic Synthesis: This compound is a key reagent in organic synthesis, facilitating the creation of complex molecules in academic and industrial laboratories.
  • Biochemical Studies: It is utilized in studies related to enzyme activity and metabolic pathways, providing insights into biological processes.

Citations