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Catalog Number:
41321
CAS Number:
57288-03-6
(S)-(-)-Aminoglutethimide
Purity:
≥ 97% (Assay)
Synonym(s):
(S)-3-(4-Aminophenyl)-3-ethylpiperidine-2,6-dione, (3S)-3-Amino-4-ethyl-4-phenylpiperidine-2,6-dione
Documents
$194.99 /500MG
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Product Information

(S)-(-)-Aminoglutethimide is a chiral compound recognized for its significant role in pharmaceutical applications, particularly in the treatment of hormone-dependent cancers. This compound acts as an aromatase inhibitor, effectively reducing estrogen levels in the body, which is crucial for managing conditions such as breast cancer. Its unique structure allows it to selectively target specific pathways, making it a valuable tool in both research and clinical settings.

In addition to its therapeutic uses, (S)-(-)-Aminoglutethimide has been explored in various studies for its potential in endocrine therapies and as a precursor in the synthesis of other bioactive compounds. Researchers appreciate its ability to facilitate the development of innovative treatments, providing a foundation for further advancements in cancer therapy. With its proven efficacy and versatility, (S)-(-)-Aminoglutethimide stands out as a compound of choice for professionals in the pharmaceutical and research industries.

Synonyms
(S)-3-(4-Aminophenyl)-3-ethylpiperidine-2,6-dione, (3S)-3-Amino-4-ethyl-4-phenylpiperidine-2,6-dione
CAS Number
57288-03-6
Purity
≥ 97% (Assay)
Molecular Formula
C13H16N2O2
Molecular Weight
232.28
MDL Number
MFCD03094024
PubChem ID
2145
Melting Point
115.5 - 119.5 °C (Lit.)
Optical Rotation
[α]20D = -160 ± 2 ° (C = 1 in MeOH)
Conditions
Store at RT
General Information
Synonyms
(S)-3-(4-Aminophenyl)-3-ethylpiperidine-2,6-dione, (3S)-3-Amino-4-ethyl-4-phenylpiperidine-2,6-dione
CAS Number
57288-03-6
Purity
≥ 97% (Assay)
Molecular Formula
C13H16N2O2
Molecular Weight
232.28
MDL Number
MFCD03094024
PubChem ID
2145
Melting Point
115.5 - 119.5 °C (Lit.)
Optical Rotation
[α]20D = -160 ± 2 ° (C = 1 in MeOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(-)-Aminoglutethimide is widely utilized in research focused on

  • Pharmaceutical Development: This compound is primarily used in the synthesis of various pharmaceuticals, particularly in the development of medications for hormone-related conditions, such as adrenal tumors.
  • Cancer Research: It plays a role in studies aimed at understanding and treating certain types of cancer, especially those influenced by steroid hormones, providing insights into potential therapeutic pathways.
  • Endocrinology: Researchers leverage its properties to investigate adrenal function and disorders, aiding in the development of treatments for conditions like Cushing's syndrome.
  • Analytical Chemistry: The compound is utilized in analytical methods to quantify steroid hormones in biological samples, enhancing the accuracy of diagnostic tests.
  • Drug Interaction Studies: It serves as a valuable tool in pharmacokinetic studies, helping scientists understand how different drugs interact within the body, which is crucial for safe medication development.

Citations