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Catalog Number:
41309
CAS Number:
62596-64-9
(S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine
Purity:
≥ 97.5% (GC)
Synonym(s):
(S)-2-Benzyl-1-tosylaziridine, (S)-1-[(4-Methylphenyl)sulfonyl]-2-(phenylmethyl)aziridine
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Product Information

(S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine is a versatile compound known for its unique structural properties and potential applications in organic synthesis and medicinal chemistry. This aziridine derivative features a benzyl group and a p-tolylsulfonyl moiety, making it a valuable intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its chiral nature allows for the development of enantiomerically pure compounds, which is crucial in the pharmaceutical industry where the efficacy and safety of drugs can depend on their stereochemistry.

Researchers have utilized (S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine in the synthesis of biologically active molecules, particularly in the creation of novel drug candidates. Its ability to participate in ring-opening reactions and its compatibility with various functional groups enhance its utility in complex organic transformations. This compound stands out for its potential to streamline synthetic pathways, reduce the number of steps in chemical processes, and improve overall yields, making it an essential tool for chemists focused on efficiency and innovation in drug development.

Synonyms
(S)-2-Benzyl-1-tosylaziridine, (S)-1-[(4-Methylphenyl)sulfonyl]-2-(phenylmethyl)aziridine
CAS Number
62596-64-9
Purity
≥ 97.5% (GC)
Molecular Formula
C16H17NO2S
Molecular Weight
287.38
MDL Number
MFCD00799479
PubChem ID
359370
Melting Point
92 - 94 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[α]20D = 8.8 ± 0.5 ° (C = 1.3 in Toluene)
Conditions
Store at RT
General Information
Synonyms
(S)-2-Benzyl-1-tosylaziridine, (S)-1-[(4-Methylphenyl)sulfonyl]-2-(phenylmethyl)aziridine
CAS Number
62596-64-9
Purity
≥ 97.5% (GC)
Molecular Formula
C16H17NO2S
Molecular Weight
287.38
MDL Number
MFCD00799479
PubChem ID
359370
Melting Point
92 - 94 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[α]20D = 8.8 ± 0.5 ° (C = 1.3 in Toluene)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine is widely utilized in research focused on:

  • Synthetic Chemistry: This compound serves as a versatile building block in the synthesis of complex organic molecules, particularly in the development of pharmaceuticals and agrochemicals.
  • Medicinal Chemistry: Its unique structure allows for the design of novel drug candidates, especially in targeting specific biological pathways, enhancing efficacy and reducing side effects.
  • Asymmetric Synthesis: The compound is valuable in asymmetric synthesis processes, enabling the production of chiral compounds with high enantiomeric purity, which is crucial in drug development.
  • Material Science: It can be used in the formulation of advanced materials, including polymers and coatings, due to its ability to modify physical properties and enhance performance.
  • Biotechnology: This chemical plays a role in the development of bioconjugates, which are essential for targeted drug delivery systems and diagnostic applications in medical research.

Citations