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Catalog Number:
39526
CAS Number:
68690-19-7
(S)-Trichostatic acid
Purity:
≥ 98% (Chiral purity, HPLC)
Synonym(s):
(S,2E,4E)-7-[4-(Dimethylamino)phenyl]-4,6-dimethyl-7-oxo-2,4-heptadienoicacid
Documents
$726.09 /200MG
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Product Information

(S)-Trichostatic acid is a potent compound recognized for its significant role in epigenetic research and therapeutic applications. This compound, also known as Trichostatin A, is a well-studied histone deacetylase (HDAC) inhibitor, making it invaluable in the fields of cancer research and neurobiology. Its unique ability to modulate gene expression through the inhibition of HDACs allows researchers to explore novel pathways in cellular differentiation and apoptosis. This property has led to its application in various studies aimed at understanding the mechanisms of cancer progression and potential treatment strategies.

In addition to its research applications, (S)-Trichostatic acid has shown promise in the development of anti-inflammatory and neuroprotective therapies. Its effectiveness in enhancing the expression of neurotrophic factors positions it as a candidate for treating neurodegenerative diseases. Researchers and industry professionals can leverage the compound's properties to develop innovative solutions in drug discovery and therapeutic interventions, making it a valuable addition to any laboratory focused on cutting-edge biomedical research.

Synonyms
(S,2E,4E)-7-[4-(Dimethylamino)phenyl]-4,6-dimethyl-7-oxo-2,4-heptadienoicacid
CAS Number
68690-19-7
Purity
≥ 98% (Chiral purity, HPLC)
Molecular Formula
C17H21NO3
Molecular Weight
287.36
MDL Number
MFCD31618158
PubChem ID
130736
Melting Point
90 - 92 °C
Appearance
White, orange or green crystalline powder
Optical Rotation
[α]20D = -147 ° (C=0.32 in MeOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(S,2E,4E)-7-[4-(Dimethylamino)phenyl]-4,6-dimethyl-7-oxo-2,4-heptadienoicacid
CAS Number
68690-19-7
Purity
≥ 98% (Chiral purity, HPLC)
Molecular Formula
C17H21NO3
Molecular Weight
287.36
MDL Number
MFCD31618158
PubChem ID
130736
Melting Point
90 - 92 °C
Appearance
White, orange or green crystalline powder
Optical Rotation
[α]20D = -147 ° (C=0.32 in MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-Trichostatic acid is widely utilized in research focused on

  • Cancer Research: This compound has shown potential as an anti-cancer agent by inhibiting histone deacetylases (HDACs), which play a crucial role in cancer cell proliferation. Researchers are exploring its efficacy in various cancer types, making it a valuable tool in oncology.
  • Epigenetics: As a histone deacetylase inhibitor, it is instrumental in studying epigenetic modifications. This application helps scientists understand gene expression regulation, providing insights into developmental biology and disease mechanisms.
  • Neuroscience: The compound is being investigated for its neuroprotective effects, particularly in neurodegenerative diseases. Its ability to modulate gene expression could lead to new therapeutic strategies for conditions like Alzheimer’s and Parkinson’s.
  • Pharmaceutical Development: (S)-Trichostatic acid serves as a lead compound in the development of new drugs. Its unique structure and mechanism of action can inspire the design of novel therapeutics targeting various diseases.
  • Biotechnology: In biotechnological applications, it is used to enhance the production of secondary metabolites in microbial cultures. This can improve yields of valuable compounds in industries such as pharmaceuticals and agriculture.

Citations