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Catalog Number:
39480
CAS Number:
136030-00-7
(1R,2S)-(+)-1-Amino-2-indanol
Purity:
≥ 98% (Assay by titration, Chiral purity, GC)
Synonym(s):
(1R,2S)-(+)-1-Amino-2-hydroxyindan
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Product Information

(1R,2S)-(+)-1-Amino-2-indanol is a versatile compound recognized for its significant role in the synthesis of various pharmaceuticals and agrochemicals. This chiral amino alcohol is particularly valued in asymmetric synthesis, where it serves as a crucial building block for the development of biologically active molecules. Its unique structure allows for the creation of compounds with specific stereochemistry, which is essential in drug design and development. Researchers have utilized (1R,2S)-(+)-1-Amino-2-indanol in the production of selective serotonin reuptake inhibitors (SSRIs) and other therapeutic agents, showcasing its potential in enhancing pharmacological efficacy.

Moreover, this compound's properties make it an excellent candidate for applications in the field of organic synthesis, particularly in the creation of chiral intermediates. Its ability to facilitate enantioselective reactions positions it as a valuable resource for chemists aiming to develop new drugs with improved safety and effectiveness profiles. The growing interest in sustainable chemistry further highlights the relevance of (1R,2S)-(+)-1-Amino-2-indanol, as it supports the development of greener synthetic pathways in pharmaceutical manufacturing.

Synonyms
(1R,2S)-(+)-1-Amino-2-hydroxyindan
CAS Number
136030-00-7
Purity
≥ 98% (Assay by titration, Chiral purity, GC)
Molecular Formula
C9H11NO
Molecular Weight
149.19
MDL Number
MFCD00216656
PubChem ID
139034
Melting Point
116 °C
Appearance
White, orange or green crystalline powder
Optical Rotation
[α]20D = 43 ° (C=1 in MeOH)
Conditions
Store at RT
General Information
Synonyms
(1R,2S)-(+)-1-Amino-2-hydroxyindan
CAS Number
136030-00-7
Purity
≥ 98% (Assay by titration, Chiral purity, GC)
Molecular Formula
C9H11NO
Molecular Weight
149.19
MDL Number
MFCD00216656
PubChem ID
139034
Melting Point
116 °C
Appearance
White, orange or green crystalline powder
Optical Rotation
[α]20D = 43 ° (C=1 in MeOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(1R,2S)-(+)-1-Amino-2-indanol is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Chiral Catalysis: It is employed as a chiral ligand in asymmetric synthesis, enhancing the selectivity and efficiency of reactions in the production of enantiomerically pure compounds.
  • Biochemical Research: Researchers use it to study enzyme interactions and mechanisms, providing insights into biological processes and potential therapeutic targets.
  • Material Science: The compound is explored for its potential applications in creating novel materials with unique properties, such as conducting polymers or sensors.
  • Natural Product Synthesis: It plays a role in the synthesis of complex natural products, aiding chemists in the development of new compounds with medicinal properties.

Citations