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Catalog Number:
39418
CAS Number:
32189-36-9
4-Chloro-D-mandelic acid
Purity:
≥ 98% (Assay by titration, GC)
Synonym(s):
(R)-2-(4-Chlorophenyl)-2-hydroxyacetic acid
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Product Information

4-Chloro-D-mandelic acid is a versatile compound recognized for its unique properties and applications in various fields, particularly in pharmaceuticals and organic synthesis. This aromatic compound features a chlorinated phenyl group, which enhances its reactivity and makes it an essential intermediate in the synthesis of chiral pharmaceuticals. Its ability to act as a chiral building block allows researchers to develop compounds with specific stereochemistry, crucial for the efficacy of many drugs.

In addition to its pharmaceutical applications, 4-Chloro-D-mandelic acid is also utilized in the production of agrochemicals and fine chemicals, where its reactivity can be harnessed for the development of novel compounds. Its distinct properties make it a valuable asset for researchers looking to innovate in drug formulation and chemical synthesis. The compound's stability and ease of handling further contribute to its appeal, ensuring that it meets the rigorous demands of both laboratory and industrial environments.

Synonyms
(R)-2-(4-Chlorophenyl)-2-hydroxyacetic acid
CAS Number
32189-36-9
Purity
≥ 98% (Assay by titration, GC)
Molecular Formula
C8H7ClO3
Molecular Weight
186.59
MDL Number
MFCD00798430
PubChem ID
10299
Melting Point
119 - 123 °C
Appearance
White or off-white crystalline powder
Optical Rotation
[α]20D = -132 to -140 ° (C=0.3 in EtOH)
Conditions
Store at RT
General Information
Synonyms
(R)-2-(4-Chlorophenyl)-2-hydroxyacetic acid
CAS Number
32189-36-9
Purity
≥ 98% (Assay by titration, GC)
Molecular Formula
C8H7ClO3
Molecular Weight
186.59
MDL Number
MFCD00798430
PubChem ID
10299
Melting Point
119 - 123 °C
Appearance
White or off-white crystalline powder
Optical Rotation
[α]20D = -132 to -140 ° (C=0.3 in EtOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Chloro-D-mandelic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-inflammatory and analgesic drugs.
  • Chiral Synthesis: Its chiral nature makes it valuable in asymmetric synthesis, allowing chemists to create specific enantiomers that are crucial in drug formulation.
  • Analytical Chemistry: Used as a standard in chromatographic techniques, it aids in the quantification of other compounds, ensuring accurate analysis in quality control processes.
  • Cosmetic Formulations: The compound is incorporated into skincare products for its potential skin-soothing properties, enhancing the effectiveness of formulations aimed at sensitive skin.
  • Research in Biochemistry: It is utilized in studies exploring metabolic pathways and enzyme interactions, providing insights into biochemical processes relevant to health and disease.

Citations