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Catalog Number:
36988
CAS Number:
51019-43-3
(R)-(-)-O-Acetylmandelic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
(R)-(-)-α-Acetoxyphenylacetic acid, (-)-O-Acetyl-D-mandelic acid
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$36.65 /25G
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Product Information

(R)-(-)-O-Acetylmandelic acid is a versatile compound widely recognized for its applications in pharmaceuticals and organic synthesis. This chiral molecule, characterized by its unique acetyloxy and phenyl groups, serves as an essential building block in the synthesis of various bioactive compounds. Its enantiomeric purity makes it particularly valuable in the development of chiral drugs, where the specific configuration can significantly influence therapeutic efficacy and safety.

In the pharmaceutical industry, (R)-(-)-O-Acetylmandelic acid is utilized in the synthesis of anti-inflammatory and analgesic agents, showcasing its potential in addressing pain management and inflammatory conditions. Additionally, its role as an intermediate in the production of other complex organic molecules highlights its importance in research and development settings. Researchers appreciate its stability and reactivity, which facilitate the creation of diverse chemical derivatives. With its proven track record and broad applicability, (R)-(-)-O-Acetylmandelic acid stands out as a crucial compound for professionals seeking reliable solutions in drug development and organic synthesis.

Synonyms
(R)-(-)-α-Acetoxyphenylacetic acid, (-)-O-Acetyl-D-mandelic acid
CAS Number
51019-43-3
Purity
≥ 99% (HPLC)
Molecular Formula
C10H10O4
Molecular Weight
194.19
MDL Number
MFCD00004249
PubChem ID
225215
Melting Point
97 - 99 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -140 to -160 ° (C = 1 in Acetone)
Conditions
Store at RT
General Information
Synonyms
(R)-(-)-α-Acetoxyphenylacetic acid, (-)-O-Acetyl-D-mandelic acid
CAS Number
51019-43-3
Purity
≥ 99% (HPLC)
Molecular Formula
C10H10O4
Molecular Weight
194.19
MDL Number
MFCD00004249
PubChem ID
225215
Melting Point
97 - 99 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -140 to -160 ° (C = 1 in Acetone)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(-)-O-Acetylmandelic acid is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the production of chiral drugs that require specific stereochemistry for efficacy.
  • Chiral Resolution: It is employed in the process of chiral resolution, helping researchers separate enantiomers in racemic mixtures, which is crucial for developing drugs with fewer side effects.
  • Analytical Chemistry: The compound is used as a standard in analytical methods, such as chromatography, to ensure accurate identification and quantification of similar compounds in complex mixtures.
  • Biochemical Research: It plays a role in studying enzyme activity and metabolic pathways, providing insights into biological processes and potential therapeutic targets.
  • Cosmetic Formulations: The compound is also found in cosmetic products, where it acts as a stabilizer or pH adjuster, enhancing product performance and shelf life.

Citations