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Catalog Number:
38214
CAS Number:
129101-54-8
Rivastigmine L-tartrate
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
3-[(S-1-(Dimethylamino)ethyl]phenyl N-Ethyl-N-methylcarbamate L-tartrate, N-Ethyl-N-methylcarbamic acid 3-[(S-1-(Dimethylamino)ethyl]phenyl ester L-tartrate
Hazmat
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$204.31 /1G
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Product Information

Rivastigmine L-tartrate is a potent reversible inhibitor of the enzyme acetylcholinesterase, making it a critical compound in the treatment of Alzheimer's disease and other dementias. This compound enhances cholinergic function by increasing the levels of acetylcholine in the brain, which is essential for memory and cognitive functions. Its unique dual-action mechanism not only inhibits acetylcholinesterase but also butyrylcholinesterase, providing a broader therapeutic effect. Rivastigmine L-tartrate is commonly utilized in pharmaceutical formulations, particularly in oral and transdermal delivery systems, offering flexibility in administration for patients with varying needs.

In addition to its primary use in neurodegenerative disorders, Rivastigmine L-tartrate has shown potential in research settings for studying cholinergic pathways and their implications in other neurological conditions. Its favorable safety profile and efficacy make it a preferred choice among healthcare professionals. The compound's solubility and stability further enhance its applicability in various formulations, ensuring consistent therapeutic outcomes for patients.

Synonyms
3-[(S-1-(Dimethylamino)ethyl]phenyl N-Ethyl-N-methylcarbamate L-tartrate, N-Ethyl-N-methylcarbamic acid 3-[(S-1-(Dimethylamino)ethyl]phenyl ester L-tartrate
CAS Number
129101-54-8
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C14H22N2O2·C4H6O6
Molecular Weight
400.43
MDL Number
MFCD03700731
PubChem ID
14254240
Melting Point
124 - 128 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = 4 - 7 ° (C=5 in Methanol)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
3-[(S-1-(Dimethylamino)ethyl]phenyl N-Ethyl-N-methylcarbamate L-tartrate, N-Ethyl-N-methylcarbamic acid 3-[(S-1-(Dimethylamino)ethyl]phenyl ester L-tartrate
CAS Number
129101-54-8
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C14H22N2O2·C4H6O6
Molecular Weight
400.43
MDL Number
MFCD03700731
PubChem ID
14254240
Melting Point
124 - 128 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = 4 - 7 ° (C=5 in Methanol)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Rivastigmine L-tartrate is widely utilized in research focused on:

  • Alzheimer's Disease Treatment: This compound is primarily used as a medication to manage symptoms of Alzheimer's disease, helping to improve cognitive function and slow disease progression.
  • Parkinson's Disease Management: It is also effective in treating dementia associated with Parkinson's disease, providing relief from cognitive decline in patients.
  • Neuropharmacological Research: Researchers use Rivastigmine L-tartrate to study its effects on neurotransmitter systems, particularly in understanding cholinergic function and its role in memory and learning.
  • Formulation Development: The compound is utilized in the development of various pharmaceutical formulations, including transdermal patches, which enhance patient compliance and provide controlled drug delivery.
  • Clinical Trials: Rivastigmine L-tartrate is frequently involved in clinical trials aimed at evaluating new treatment protocols for neurodegenerative diseases, contributing to advancements in therapeutic strategies.