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Catalog Number:
38198
CAS Number:
257933-82-7
Pelitinib
Purity:
≥ 97% (HPLC)
Synonym(s):
EKB 569, (2E-N-[4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-dimethylamino-2-butenamide
Hazmat
Documents
$261.99 /25MG
Pack Size Availability Price
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Product Information

Pelitinib is a potent small molecule inhibitor designed to target specific tyrosine kinases, particularly in the treatment of various cancers. This compound has garnered attention for its ability to selectively inhibit the activity of the epidermal growth factor receptor (EGFR), making it a valuable asset in oncology research and therapeutic applications. With its unique structure, Pelitinib demonstrates promising efficacy against tumors that exhibit resistance to conventional therapies, providing a new avenue for treatment in challenging cases. Researchers and industry professionals can leverage Pelitinib in drug development processes, particularly in studies focusing on targeted cancer therapies and personalized medicine.

The compound's favorable pharmacokinetic properties enhance its potential for clinical use, allowing for effective dosing regimens. Pelitinib has shown significant activity in preclinical models, paving the way for further exploration in clinical trials. Its specificity and potency position it as a leading candidate in the ongoing fight against cancer, particularly for patients with EGFR mutations. As the field of targeted therapies evolves, Pelitinib stands out for its ability to address unmet medical needs, making it an essential compound for researchers and pharmaceutical developers alike.

Synonyms
EKB 569, (2E-N-[4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-dimethylamino-2-butenamide
CAS Number
257933-82-7
Purity
≥ 97% (HPLC)
Molecular Formula
C24H23ClFN5O2
Molecular Weight
467.93
MDL Number
MFCD09837868
PubChem ID
216467
Melting Point
197 - 199 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at < 0 °C
General Information
Synonyms
EKB 569, (2E-N-[4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-dimethylamino-2-butenamide
CAS Number
257933-82-7
Purity
≥ 97% (HPLC)
Molecular Formula
C24H23ClFN5O2
Molecular Weight
467.93
MDL Number
MFCD09837868
PubChem ID
216467
Melting Point
197 - 199 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Pelitinib is widely utilized in research focused on:

  • Cancer Treatment: Pelitinib is primarily studied for its potential in treating various types of cancer, particularly non-small cell lung cancer (NSCLC). Its targeted action on specific cancer cell pathways makes it a promising candidate for personalized medicine.
  • Drug Development: Researchers are exploring Pelitinib as a lead compound for developing new anti-cancer drugs. Its unique structure allows for modifications that can enhance efficacy and reduce side effects compared to traditional chemotherapy agents.
  • Combination Therapies: Pelitinib is being investigated in combination with other therapies to improve treatment outcomes. This approach can help overcome resistance mechanisms that often limit the effectiveness of single-agent treatments.
  • Biomarker Research: The use of Pelitinib in clinical studies is aiding the identification of biomarkers that predict patient responses to treatment, which is crucial for optimizing therapy and improving patient outcomes.
  • Pharmacokinetic Studies: Pelitinib's pharmacokinetic profile is being analyzed to understand its absorption, distribution, metabolism, and excretion in the body, providing valuable information for dosage optimization and safety assessments.