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Catalog Number:
38153
CAS Number:
101-26-8
Pyridostigmine bromide
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
3-(Dimethylcarbamoyloxy)-1-methylpyridinium bromide
Hazmat
Documents
$256.78 /5G
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Product Information

Pyridostigmine bromide is a potent reversible inhibitor of the enzyme acetylcholinesterase, making it a critical compound in the treatment of myasthenia gravis and other neuromuscular disorders. This compound enhances neuromuscular transmission by increasing the availability of acetylcholine at the neuromuscular junction, thereby improving muscle strength and endurance. Its unique properties allow it to be utilized not only in therapeutic applications but also in research settings to study cholinergic mechanisms and the effects of acetylcholine modulation.

In addition to its medical applications, Pyridostigmine bromide has been explored for its potential use in military settings as a protective agent against nerve agents. Its ability to counteract the effects of certain toxic agents underscores its importance in both healthcare and defense sectors. Researchers and industry professionals appreciate its stability and efficacy, making it a valuable compound for both clinical and experimental use.

Synonyms
3-(Dimethylcarbamoyloxy)-1-methylpyridinium bromide
CAS Number
101-26-8
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C9H13BrN2O2
Molecular Weight
261.12
MDL Number
MFCD00079283
PubChem ID
7550
Melting Point
153 - 157 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
3-(Dimethylcarbamoyloxy)-1-methylpyridinium bromide
CAS Number
101-26-8
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C9H13BrN2O2
Molecular Weight
261.12
MDL Number
MFCD00079283
PubChem ID
7550
Melting Point
153 - 157 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Pyridostigmine bromide is widely utilized in research focused on:

  • Treatment of Myasthenia Gravis: This compound is primarily used to manage symptoms of myasthenia gravis, a neuromuscular disorder. It enhances communication between nerves and muscles, improving muscle strength.
  • Military Medicine: Pyridostigmine bromide is used as a prophylactic treatment against nerve agent exposure. It helps protect soldiers by inhibiting the breakdown of acetylcholine, counteracting the effects of certain chemical agents.
  • Research in Neuropharmacology: Researchers study this compound to understand its mechanism of action and effects on the nervous system, providing insights into potential treatments for other neurological conditions.
  • Veterinary Medicine: It is also applied in veterinary practices to treat certain neuromuscular disorders in animals, showcasing its versatility across species.
  • Pharmacological Studies: The compound serves as a valuable tool in pharmacological studies to evaluate drug interactions and the effects of cholinergic agents, aiding in the development of new therapies.

Citations