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Catalog Number:
38138
CAS Number:
103639-04-9
Ondansetron hydrochloride dihydrate
Grade:
Meets USP Specification
Purity:
98 - 102% (Assay on anhydrous basis)
Synonym(s):
1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride dihydrate
Hazmat
Documents
$20.00 /1G
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Product Information

Ondansetron hydrochloride dihydrate is a potent antiemetic agent primarily used in the management of nausea and vomiting associated with chemotherapy, radiation therapy, and postoperative recovery. This compound works by selectively antagonizing serotonin receptors, effectively blocking the action of serotonin, which is a key mediator in the vomiting reflex. Its high efficacy and rapid onset make it a preferred choice in clinical settings, providing relief to patients undergoing challenging treatments.

In addition to its primary use in oncology, Ondansetron hydrochloride dihydrate is also utilized in various research applications, including studies focused on gastrointestinal disorders and neuropharmacology. Its unique properties, such as excellent solubility and stability, enhance its versatility in pharmaceutical formulations. Researchers and healthcare professionals appreciate its ability to improve patient comfort and compliance, making it an essential compound in both therapeutic and investigational contexts.

Synonyms
1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride dihydrate
CAS Number
103639-04-9
Purity
98 - 102% (Assay on anhydrous basis)
Grade
Meets USP Specification
Molecular Formula
C18H19N3O·HCl·2H2O
Molecular Weight
365.86
MDL Number
MFCD00374371
PubChem ID
59774
Melting Point
176 - 180 °C (Lit.)
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride dihydrate
CAS Number
103639-04-9
Purity
98 - 102% (Assay on anhydrous basis)
Grade
Meets USP Specification
Molecular Formula
C18H19N3O·HCl·2H2O
Molecular Weight
365.86
MDL Number
MFCD00374371
PubChem ID
59774
Melting Point
176 - 180 °C (Lit.)
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ondansetron hydrochloride dihydrate is widely utilized in research focused on:

  • Anti-Nausea Treatment: Commonly used in hospitals and clinics to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery, providing significant relief to patients.
  • Pharmaceutical Development: Serves as a key compound in the formulation of antiemetic drugs, allowing researchers to explore new delivery methods and dosage forms for enhanced patient compliance.
  • Clinical Trials: Frequently included in clinical studies to evaluate its effectiveness and safety in various patient populations, contributing to evidence-based medicine.
  • Research on Serotonin Receptors: Used in laboratory settings to study the interaction with serotonin receptors, aiding in the understanding of various neurological and gastrointestinal disorders.
  • Veterinary Medicine: Applied in veterinary practices to manage nausea and vomiting in animals undergoing treatment, showcasing its versatility beyond human medicine.

Citations