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Catalog Number:
38126
CAS Number:
23327-57-3
Nefopam hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride
Hazmat
Documents
$68.20 /1G
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Product Information

Nefopam hydrochloride is a potent analgesic compound recognized for its unique mechanism of action that distinguishes it from traditional opioids. This non-opioid analgesic is primarily utilized in the management of moderate to severe pain, making it a valuable alternative for patients who may be at risk of opioid dependence. Its efficacy is attributed to its ability to inhibit the reuptake of neurotransmitters such as norepinephrine, serotonin, and dopamine, which play crucial roles in pain modulation.

In clinical settings, Nefopam hydrochloride has been effectively employed in postoperative pain management and for chronic pain conditions, providing relief without the common side effects associated with opioids, such as respiratory depression and constipation. Researchers and healthcare professionals appreciate its versatility, as it can be administered via oral or intravenous routes, allowing for tailored treatment plans. Additionally, its favorable safety profile and minimal risk of addiction make it an attractive option for pain management in various patient populations.

Synonyms
5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride
CAS Number
23327-57-3
Purity
≥ 98% (HPLC)
Molecular Formula
C17H19NO·HCl
Molecular Weight
289.8
MDL Number
MFCD00012750
PubChem ID
31872
Melting Point
250 - 252 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride
CAS Number
23327-57-3
Purity
≥ 98% (HPLC)
Molecular Formula
C17H19NO·HCl
Molecular Weight
289.8
MDL Number
MFCD00012750
PubChem ID
31872
Melting Point
250 - 252 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nefopam hydrochloride is widely utilized in research focused on:

  • Pain Management: This compound is primarily used as a non-opioid analgesic, providing effective pain relief without the risk of addiction associated with opioids. It is particularly beneficial in postoperative settings.
  • Neurological Research: Researchers explore its effects on the central nervous system, as it has been shown to influence neurotransmitter systems, making it valuable in studies related to depression and anxiety.
  • Pharmaceutical Development: Nefopam hydrochloride serves as a model compound in the development of new analgesics, allowing scientists to investigate its pharmacokinetics and pharmacodynamics for improved drug formulations.
  • Veterinary Medicine: This chemical is also applied in veterinary practices for pain management in animals, providing an alternative to traditional pain relief methods.
  • Clinical Trials: It is frequently used in clinical trials to assess its efficacy and safety in various pain-related conditions, contributing to the advancement of pain management therapies.

Citations