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Catalog Number:
38091
CAS Number:
51-60-5
Neostigmine methyl sulfate
Synonym(s):
(3-Dimethylcarbamoyloxyphenyl)trimethylammonium methyl sulfate, (3-Hydroxyphenyl)trimethylammonium methyl sulfate dimethylcarbamate
Hazmat
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Product Information

Neostigmine methyl sulfate is a potent reversible inhibitor of the enzyme acetylcholinesterase, making it a valuable compound in both medical and research applications. This chemical is primarily utilized in the treatment of myasthenia gravis, a neuromuscular disorder characterized by weakness and rapid fatigue of voluntary muscles. By enhancing the levels of acetylcholine at neuromuscular junctions, Neostigmine methyl sulfate effectively improves muscle strength and function, providing significant relief for patients. Additionally, it is used in anesthesia to reverse the effects of muscle relaxants, ensuring safer surgical procedures.

In research settings, Neostigmine methyl sulfate serves as a critical tool for studying cholinergic signaling pathways and the pharmacological effects of acetylcholine. Its unique properties allow for the exploration of neurodegenerative diseases and potential therapeutic interventions. With its established efficacy and versatility, Neostigmine methyl sulfate stands out as an essential compound for both clinical and laboratory applications, offering researchers and healthcare professionals a reliable solution for enhancing neuromuscular function.

Synonyms
(3-Dimethylcarbamoyloxyphenyl)trimethylammonium methyl sulfate, (3-Hydroxyphenyl)trimethylammonium methyl sulfate dimethylcarbamate
CAS Number
51-60-5
Molecular Formula
C13H22N2O6S
Molecular Weight
334.39
MDL Number
MFCD00011796
PubChem ID
5824
Melting Point
145 - 149 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(3-Dimethylcarbamoyloxyphenyl)trimethylammonium methyl sulfate, (3-Hydroxyphenyl)trimethylammonium methyl sulfate dimethylcarbamate
CAS Number
51-60-5
Molecular Formula
C13H22N2O6S
Molecular Weight
334.39
MDL Number
MFCD00011796
PubChem ID
5824
Melting Point
145 - 149 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Neostigmine methyl sulfate is widely utilized in research focused on:

  • Medical Treatment: It is primarily used in the treatment of myasthenia gravis, a condition that leads to muscle weakness. By enhancing communication between nerves and muscles, it helps improve muscle strength.
  • Anesthesia: In surgical settings, this compound is employed to reverse the effects of muscle relaxants used during anesthesia, aiding in quicker recovery post-surgery.
  • Research in Neuropharmacology: Researchers study its effects on neurotransmission, providing insights into nerve function and potential treatments for neurological disorders.
  • Veterinary Medicine: Neostigmine methyl sulfate is also used in veterinary practices, particularly for treating certain conditions in animals that affect muscle control.
  • Pharmaceutical Development: It serves as a model compound in drug formulation studies, helping scientists understand drug interactions and efficacy in various formulations.

Citations