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Catalog Number:
38085
CAS Number:
65271-80-9
Mitoxantrone
Purity:
≥ 97% (HPLC)
Synonym(s):
1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone, 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthracene-9,10-dione
Hazmat
Documents
$97.25 /200MG
Pack Size Availability Price
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Product Information

Mitoxantrone is a synthetic anthracenedione derivative known for its potent antineoplastic properties, primarily utilized in the treatment of various cancers, including leukemia and breast cancer. This compound functions as an intercalating agent, disrupting DNA replication and transcription, which is crucial for cancer cell proliferation. Its unique structure allows for effective targeting of rapidly dividing cells, making it a valuable option in chemotherapy regimens. Mitoxantrone is also recognized for its application in treating multiple sclerosis, where it helps to reduce the frequency of relapses and slow disease progression.

Researchers and healthcare professionals appreciate Mitoxantrone for its ability to provide therapeutic benefits while maintaining a manageable side effect profile compared to other chemotherapeutic agents. Its versatility in both oncology and neurology highlights its significance in modern medical treatments. With ongoing studies exploring its efficacy in combination therapies, Mitoxantrone continues to hold promise for enhancing patient outcomes in challenging medical conditions.

Synonyms
1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone, 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthracene-9,10-dione
CAS Number
65271-80-9
Purity
≥ 97% (HPLC)
Molecular Formula
C22H28N4O6
Molecular Weight
444.49
MDL Number
MFCD00242942
PubChem ID
4212
Melting Point
170 - 174 °C
Appearance
Light yellow to amber to dark green powder to crystal
Conditions
Store at < -20 °C
General Information
Synonyms
1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone, 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthracene-9,10-dione
CAS Number
65271-80-9
Purity
≥ 97% (HPLC)
Molecular Formula
C22H28N4O6
Molecular Weight
444.49
MDL Number
MFCD00242942
PubChem ID
4212
Melting Point
170 - 174 °C
Appearance
Light yellow to amber to dark green powder to crystal
Conditions
Store at < -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mitoxantrone is widely utilized in research focused on:

  • Cancer Treatment: This compound is primarily used as a chemotherapy agent for treating various types of cancer, including leukemia and breast cancer. It works by interfering with the DNA of cancer cells, preventing their growth and reproduction.
  • Multiple Sclerosis Therapy: Mitoxantrone is also employed in the treatment of multiple sclerosis (MS). It helps reduce the frequency of relapses and slows the progression of disability in patients.
  • Cardiotoxicity Research: Researchers study the cardiotoxic effects of mitoxantrone to better understand its impact on heart health, which can lead to improved patient management strategies during chemotherapy.
  • Combination Therapy Studies: It is often used in combination with other drugs to enhance therapeutic efficacy. This approach allows researchers to explore synergistic effects and optimize treatment regimens for better outcomes.
  • Pharmaceutical Development: Mitoxantrone serves as a model compound in drug formulation studies, helping scientists develop more effective delivery systems and dosage forms for cancer therapies.

Citations