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Catalog Number:
38043
CAS Number:
5370-01-4
Mexiletine hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
1-(2,6-Dimethylphenoxy)-2-propylamine hydrochloride
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Product Information

Mexiletine hydrochloride is a potent antiarrhythmic agent primarily used in the management of ventricular arrhythmias. This compound functions by stabilizing cardiac membranes, making it invaluable in treating conditions such as ventricular tachycardia and other heart rhythm disorders. Its unique mechanism of action allows for effective modulation of sodium channels, which is crucial for maintaining normal heart rhythm. Researchers and healthcare professionals appreciate Mexiletine hydrochloride for its oral bioavailability and rapid onset of action, making it a preferred choice in acute and chronic settings.

In addition to its primary use in cardiology, Mexiletine hydrochloride has shown promise in treating neuropathic pain, particularly in conditions like diabetic neuropathy and postherpetic neuralgia. Its ability to alleviate pain while minimizing side effects compared to traditional analgesics makes it a valuable option in pain management protocols. The compound's versatility and efficacy in both cardiac and pain management applications highlight its significance in therapeutic practices, providing healthcare professionals with a reliable tool for improving patient outcomes.

Synonyms
1-(2,6-Dimethylphenoxy)-2-propylamine hydrochloride
CAS Number
5370-01-4
Purity
≥ 98% (HPLC)
Molecular Formula
C11H17NO·HCl
Molecular Weight
215.72
MDL Number
MFCD00216024
PubChem ID
21467
Melting Point
200 - 205 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-(2,6-Dimethylphenoxy)-2-propylamine hydrochloride
CAS Number
5370-01-4
Purity
≥ 98% (HPLC)
Molecular Formula
C11H17NO·HCl
Molecular Weight
215.72
MDL Number
MFCD00216024
PubChem ID
21467
Melting Point
200 - 205 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mexiletine hydrochloride is widely utilized in research focused on:

  • Cardiac Arrhythmia Treatment: Primarily used to manage ventricular arrhythmias, providing an alternative for patients who may not respond well to other antiarrhythmic medications.
  • Neuropathic Pain Management: Employed in clinical settings to alleviate chronic pain associated with conditions like diabetic neuropathy, offering a unique mechanism of action compared to traditional pain relievers.
  • Research in Pharmacology: Used in studies to understand drug interactions and pharmacokinetics, helping researchers develop better therapeutic strategies for heart conditions.
  • Veterinary Medicine: Sometimes prescribed for animals with similar cardiac issues, showcasing its versatility beyond human medicine.
  • Formulation Development: In pharmaceutical research, it serves as a model compound for developing new formulations and delivery methods, aiding in the advancement of drug delivery technologies.

Citations