Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
38018
CAS Number:
187164-19-8
Luliconazole
Purity:
≥ 98% (HPLC)
Synonym(s):
(2E)-2-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-(1H-imidazol-1-yl)acetonitrile, NND 502
Documents
$220.33 /250MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Luliconazole is a potent antifungal agent recognized for its efficacy against a variety of dermatophytes and yeast infections. This compound is particularly valuable in the treatment of skin conditions such as tinea pedis (athlete's foot), tinea corporis (ringworm), and tinea cruris (jock itch). Its unique mechanism of action involves the inhibition of fungal ergosterol synthesis, which is crucial for maintaining fungal cell membrane integrity. This makes Luliconazole a preferred choice for topical formulations, providing targeted treatment with minimal systemic absorption, thereby reducing potential side effects.

In addition to its therapeutic applications, Luliconazole is gaining attention in research settings for its potential in developing new antifungal therapies. Its favorable safety profile and effectiveness make it a compelling candidate for further studies aimed at combating resistant fungal strains. With a growing need for effective antifungal treatments, Luliconazole stands out as a reliable option for both healthcare professionals and researchers looking to enhance patient outcomes in dermatological care.

Synonyms
(2E)-2-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-(1H-imidazol-1-yl)acetonitrile, NND 502
CAS Number
187164-19-8
Purity
≥ 98% (HPLC)
Molecular Formula
C14H9Cl2N3S2
Molecular Weight
354.27
MDL Number
MFCD00953915
PubChem ID
53394969
Melting Point
150 - 154 °C
Appearance
White to orange to green powder to crystal
Optical Rotation
[a]20D = -48 to -53 ° (C=1, DMF)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(2E)-2-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-(1H-imidazol-1-yl)acetonitrile, NND 502
CAS Number
187164-19-8
Purity
≥ 98% (HPLC)
Molecular Formula
C14H9Cl2N3S2
Molecular Weight
354.27
MDL Number
MFCD00953915
PubChem ID
53394969
Melting Point
150 - 154 °C
Appearance
White to orange to green powder to crystal
Optical Rotation
[a]20D = -48 to -53 ° (C=1, DMF)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Luliconazole is widely utilized in research focused on:

  • Antifungal Treatments: This compound is primarily used in dermatology for treating fungal infections, particularly those caused by dermatophytes and yeast. Its effectiveness in topical formulations makes it a preferred choice for patients.
  • Pharmaceutical Development: Researchers are exploring luliconazole for its potential in developing new antifungal medications. Its unique mechanism of action offers a promising alternative to existing treatments.
  • Veterinary Medicine: Luliconazole is also being investigated for use in animals, particularly in treating skin infections in pets. This application highlights its versatility and effectiveness across species.
  • Cosmetic Formulations: The compound is being incorporated into skincare products aimed at preventing fungal infections, providing an added benefit for consumers concerned about skin health.
  • Research on Resistance Mechanisms: Scientists are studying luliconazole to understand how fungi develop resistance to antifungal agents, which is crucial for developing more effective treatments in the future.

Citations