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Catalog Number:
38014
CAS Number:
144481-98-1
Landiolol hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
4-[(2S)-2-Hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-benzenepropanoic acid [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester hydrochloride
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$200.30 /50MG
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Product Information

Landiolol hydrochloride is a potent and selective beta-1 adrenergic antagonist, primarily utilized in the management of tachyarrhythmias and perioperative heart rate control. This compound is particularly beneficial in clinical settings due to its rapid onset and short duration of action, making it ideal for acute situations where immediate heart rate control is required. Its unique structure allows for effective modulation of heart rate without significantly impacting blood pressure, which is crucial for patients with cardiovascular concerns.

In addition to its therapeutic applications, landiolol hydrochloride has been explored in research settings for its potential in studying cardiac function and pharmacological responses. Its safety profile and efficacy make it a valuable tool for both clinicians and researchers. The compound's ability to provide rapid heart rate control while minimizing side effects distinguishes it from other beta-blockers, enhancing its appeal in both hospital and outpatient settings.

Synonyms
4-[(2S)-2-Hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-benzenepropanoic acid [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester hydrochloride
CAS Number
144481-98-1
Purity
≥ 98% (HPLC)
Molecular Formula
C25H39N3O8·HCl
Molecular Weight
546.06
MDL Number
MFCD00911043
PubChem ID
23118722
Melting Point
124 - 128 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
4-[(2S)-2-Hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-benzenepropanoic acid [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester hydrochloride
CAS Number
144481-98-1
Purity
≥ 98% (HPLC)
Molecular Formula
C25H39N3O8·HCl
Molecular Weight
546.06
MDL Number
MFCD00911043
PubChem ID
23118722
Melting Point
124 - 128 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Landiolol hydrochloride is widely utilized in research focused on:

  • Cardiovascular Medicine: This compound is primarily used as a rapid-acting beta-blocker to manage tachycardia and hypertension during surgical procedures, providing quick heart rate control.
  • Anesthesia: In the field of anesthesiology, landiolol is employed to stabilize heart rates in patients undergoing surgery, ensuring safer anesthesia management and reducing perioperative complications.
  • Clinical Trials: Researchers use landiolol hydrochloride in clinical studies to evaluate its efficacy and safety in various cardiac conditions, contributing to advancements in treatment protocols.
  • Pharmaceutical Development: The compound serves as a reference standard in the development of new beta-blockers, allowing for comparative studies and formulation optimization.
  • Emergency Medicine: Its rapid onset of action makes it valuable in emergency settings for acute heart rate control, providing healthcare professionals with a reliable option for urgent interventions.

Citations