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Catalog Number:
37990
CAS Number:
134678-17-4
Lamivudine
Purity:
≥ 98% (HPLC)
Synonym(s):
3TC, (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
Documents
$18.53 /100MG
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Product Information

Lamivudine is a potent nucleoside reverse transcriptase inhibitor (NRTI) widely utilized in the treatment of HIV and chronic hepatitis B infections. This compound is recognized for its ability to inhibit viral replication, making it a critical component in antiretroviral therapy regimens. Lamivudine's unique structure allows for effective incorporation into viral DNA, leading to termination of the viral replication process. Its efficacy, combined with a favorable safety profile, has made it a preferred choice among healthcare professionals for managing these viral infections.

In addition to its primary applications in HIV and hepatitis B treatment, Lamivudine is also being explored for potential use in other viral infections and as part of combination therapies to enhance treatment outcomes. Researchers appreciate its relatively low resistance profile compared to other NRTIs, which can lead to improved long-term efficacy in patients. With ongoing studies, Lamivudine continues to hold promise in expanding therapeutic options for viral infections, making it a valuable asset in both clinical and research settings.

Synonyms
3TC, (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
CAS Number
134678-17-4
Purity
≥ 98% (HPLC)
Molecular Formula
C8H11N3O3S
Molecular Weight
229.25
MDL Number
MFCD00869739
PubChem ID
3877
Melting Point
173 - 179 °C
Appearance
White to off-white to light yellow to beige crystals or powder
Optical Rotation
[a]20D = -137 to -148 ° (C=1 in Methanol)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
3TC, (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
CAS Number
134678-17-4
Purity
≥ 98% (HPLC)
Molecular Formula
C8H11N3O3S
Molecular Weight
229.25
MDL Number
MFCD00869739
PubChem ID
3877
Melting Point
173 - 179 °C
Appearance
White to off-white to light yellow to beige crystals or powder
Optical Rotation
[a]20D = -137 to -148 ° (C=1 in Methanol)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Lamivudine is widely utilized in research focused on:

  • Antiviral Therapy: Primarily used in the treatment of HIV/AIDS, Lamivudine helps to suppress viral replication, improving patient outcomes and quality of life.
  • Hepatitis B Treatment: It is effective in managing chronic Hepatitis B infections, reducing liver inflammation and preventing disease progression.
  • Combination Therapy: Often combined with other antiretroviral drugs, it enhances the efficacy of treatment regimens, making it a cornerstone in HIV therapy.
  • Research on Drug Resistance: Lamivudine is a key compound in studies aimed at understanding and overcoming drug resistance in viral infections, providing insights for developing more effective treatments.
  • Pharmaceutical Development: Its properties are explored in the development of new formulations and delivery methods, aiming to improve patient adherence and therapeutic outcomes.

Citations