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Catalog Number:
37962
CAS Number:
138402-11-6
Irbesartan
Purity:
≥ 98% (HPLC)
Synonym(s):
2-Butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one, Avapro
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Product Information

Irbesartan is a potent angiotensin II receptor antagonist primarily used in the management of hypertension and heart failure. This compound is recognized for its ability to effectively lower blood pressure by inhibiting the action of angiotensin II, a hormone that constricts blood vessels. Its unique structure allows for selective binding to the AT1 receptor, making it a preferred choice in therapeutic applications. Irbesartan is also utilized in the treatment of diabetic nephropathy, showcasing its versatility in addressing various cardiovascular and renal conditions.

Researchers and healthcare professionals appreciate Irbesartan for its favorable pharmacokinetic profile, which includes a long half-life and high bioavailability, allowing for once-daily dosing. This enhances patient compliance and provides sustained therapeutic effects. Additionally, Irbesartan has been studied for its potential benefits in reducing the risk of stroke and myocardial infarction, making it a valuable option in cardiovascular health management. Its efficacy and safety profile make it a trusted choice in clinical settings, providing significant benefits to patients with hypertension and related disorders.

Synonyms
2-Butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one, Avapro
CAS Number
138402-11-6
Purity
≥ 98% (HPLC)
Molecular Formula
C25H28N6O
Molecular Weight
428.54
MDL Number
MFCD00864464
PubChem ID
3749
Melting Point
184 - 188 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one, Avapro
CAS Number
138402-11-6
Purity
≥ 98% (HPLC)
Molecular Formula
C25H28N6O
Molecular Weight
428.54
MDL Number
MFCD00864464
PubChem ID
3749
Melting Point
184 - 188 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Irbesartan is widely utilized in research focused on:

  • Hypertension Management: Commonly prescribed to lower high blood pressure, helping to reduce the risk of heart disease and stroke.
  • Cardiovascular Health: Used in studies examining its effects on heart function and overall cardiovascular health, particularly in patients with diabetes.
  • Kidney Protection: Investigated for its protective effects on kidney function in patients with chronic kidney disease, especially those with hypertension.
  • Combination Therapies: Explored in combination with other antihypertensive agents to enhance efficacy and improve patient outcomes.
  • Research on Side Effects: Analyzed for potential side effects and interactions with other medications, providing valuable insights for healthcare providers.

Documents

Safety Data Sheets (SDS)

The SDS provides comprehensive safety information on handling, storage, and disposal of the product.

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Safety Data Sheets (SDS)

The SDS provides comprehensive safety information on handling, storage, and disposal of the product.

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Product Specification (PS)

The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

*Catalog Number
The Catalog Number is a five-digit number located on the product label near the product name, and also in your order confirmation email. Exclude any hyphens or size information. Ex. 01578
*Lot Number
The Lot Number is a multi-digit number that can be found on the product label or invoice. Ex. 12345-12345
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Certificates Of Origin (COO)

This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.

*Catalog Number
The Catalog Number is a five-digit number located on the product label near the product name, and also in your order confirmation email. Exclude any hyphens or size information. Ex. 01578
*Lot Number
The Lot Number is a multi-digit number that can be found on the product label or invoice. Ex. 12345-12345
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