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Catalog Number:
37956
CAS Number:
84625-61-6
Itraconazole
Grade:
USP
Purity:
98 - 102% (Assay on anhydrous basis)
Synonym(s):
Oriconazole, Sporanox
Documents
$137.41 /5G
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Product Information

Itraconazole is a potent antifungal agent widely recognized for its effectiveness in treating a variety of fungal infections. This compound is particularly valuable in the medical field, where it is utilized to combat conditions such as aspergillosis, blastomycosis, and histoplasmosis. Its unique mechanism of action involves inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, which ultimately leads to cell death. Researchers and healthcare professionals appreciate Itraconazole for its broad spectrum of activity against both systemic and superficial fungal infections, making it a go-to choice in clinical settings.

In addition to its therapeutic applications, Itraconazole is also employed in agricultural practices to protect crops from fungal pathogens, thereby enhancing yield and quality. Its stability and efficacy in various formulations, including oral and intravenous preparations, further underscore its versatility. With ongoing research into its potential uses, Itraconazole continues to hold promise for new applications in both medicine and agriculture, making it a valuable compound for professionals in these fields.

Synonyms
Oriconazole, Sporanox
CAS Number
84625-61-6
Purity
98 - 102% (Assay on anhydrous basis)
Grade
USP
Molecular Formula
C35H38Cl2N8O4
Molecular Weight
705.64
MDL Number
MFCD00870168
PubChem ID
3793
Melting Point
166 - 170 °C (Lit.)
Appearance
White to almost white powder
Optical Rotation
[a]20D = -0.10 to 0.10 °
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Oriconazole, Sporanox
CAS Number
84625-61-6
Purity
98 - 102% (Assay on anhydrous basis)
Grade
USP
Molecular Formula
C35H38Cl2N8O4
Molecular Weight
705.64
MDL Number
MFCD00870168
PubChem ID
3793
Melting Point
166 - 170 °C (Lit.)
Appearance
White to almost white powder
Optical Rotation
[a]20D = -0.10 to 0.10 °
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Itraconazole is widely utilized in research focused on:

  • Antifungal Treatments: Commonly prescribed for various fungal infections, particularly in immunocompromised patients, it offers a reliable option for treating conditions like aspergillosis and candidiasis.
  • Veterinary Medicine: Used in veterinary practices, it helps in treating fungal infections in animals, providing a critical tool for pet health and livestock management.
  • Pharmaceutical Development: Researchers leverage its properties to develop new formulations and delivery methods, enhancing the effectiveness of antifungal therapies.
  • Oncology Research: Emerging studies suggest itraconazole may have anti-cancer properties, making it a candidate for combination therapies in cancer treatment.
  • Dermatology Applications: Its effectiveness against skin fungal infections makes it a valuable treatment option in dermatological practices, improving patient outcomes.

Citations