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Catalog Number:
37955
CAS Number:
26807-65-8
Indapamide
Purity:
≥ 97% (HPLC)
Synonym(s):
1-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline
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Product Information

Indapamide is a potent thiazide-like diuretic widely used in the management of hypertension and edema associated with heart failure. This compound is recognized for its ability to enhance renal excretion of sodium and water, effectively reducing blood pressure and alleviating fluid retention. Indapamide's unique structure allows it to provide a dual action: it not only acts as a diuretic but also possesses vasodilatory properties, making it particularly beneficial for patients with cardiovascular conditions.

In clinical settings, Indapamide is often preferred due to its favorable side effect profile and once-daily dosing, which improves patient compliance. Its application extends beyond hypertension treatment; it is also utilized in the management of certain types of kidney disorders. Researchers are exploring its potential in various therapeutic areas, including metabolic syndrome and heart failure, highlighting its versatility and importance in modern pharmacotherapy.

Synonyms
1-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline
CAS Number
26807-65-8
Purity
≥ 97% (HPLC)
Molecular Formula
C16H16ClN3O3S
Molecular Weight
365.83
MDL Number
MFCD00079375
PubChem ID
3702
Melting Point
167 - 173 °C
Appearance
White to orange to green powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline
CAS Number
26807-65-8
Purity
≥ 97% (HPLC)
Molecular Formula
C16H16ClN3O3S
Molecular Weight
365.83
MDL Number
MFCD00079375
PubChem ID
3702
Melting Point
167 - 173 °C
Appearance
White to orange to green powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Indapamide is widely utilized in research focused on:

  • Hypertension Treatment: Commonly prescribed as a diuretic, it helps lower blood pressure by promoting the excretion of sodium and water, making it effective for patients with hypertension.
  • Heart Failure Management: Indapamide is beneficial for patients with congestive heart failure, as it reduces fluid overload, improving heart function and quality of life.
  • Kidney Health: It aids in managing conditions like edema associated with kidney disorders, helping to reduce swelling and improve kidney function.
  • Research in Cardiovascular Health: Studies often explore its effects on cardiovascular risk factors, providing valuable insights into heart health and potential preventive measures.
  • Combination Therapy: Frequently used in conjunction with other antihypertensive agents, it enhances the effectiveness of treatment regimens, offering a synergistic approach to managing high blood pressure.

Citations